FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1998147949> ?p ?o ?g. }

• W1998147949 endingPage "657" @default.
• W1998147949 startingPage "651" @default.
• W1998147949 abstract "Repeated administration of cocaine produces sensitization to its locomotor-activating effects and increases the rate at which cocaine self-administration behavior is acquired. Methylphenidate is administered clinically on a daily basis, predominantly to children and adolescents, for the treatment of attention-deficit hyperactivity disorder (ADHD). It has been demonstrated previously that pretreatment with methylphenidate administered to periadolescent rats decreased the latency to acquisition of cocaine self-administration. Since methylphenidate is often also administered to adults with ADHD, the present study was conducted to determine the effects of prior administration of methylphenidate (5 or 20 mg/kg/day for 9 days) to adult rats on the rate of acquisition for cocaine self-administration (0.25 mg/kg/infusion). The higher dose of methylphenidate significantly decreased the latency for acquisition of this behavior, suggesting that the rats were sensitized to the reinforcing effects of cocaine after treatment with methylphenidate. These findings add to the growing body of evidence suggesting cross-sensitization between the behavioral effects of psychostimulants. Further, insofar as self-administration is a reliable measure of abuse liability, these data suggest that a short-duration pretreatment with a high dose of methylphenidate to adults increases vulnerability to cocaine abuse." @default.
• W1998147949 created "2016-06-24" @default.
• W1998147949 creator A5006357330 @default.
• W1998147949 creator A5026011651 @default.
• W1998147949 date "2002-06-01" @default.
• W1998147949 modified "2023-10-03" @default.
• W1998147949 title "Pretreatment with methylphenidate sensitizes rats to the reinforcing effects of cocaine" @default.
• W1998147949 cites W1965719218 @default.
• W1998147949 cites W1973667619 @default.
• W1998147949 cites W1977006488 @default.
• W1998147949 cites W1978012897 @default.
• W1998147949 cites W1980767612 @default.
• W1998147949 cites W1982114367 @default.
• W1998147949 cites W1985484876 @default.
• W1998147949 cites W1988196752 @default.
• W1998147949 cites W2019179515 @default.
• W1998147949 cites W2021284936 @default.
• W1998147949 cites W2021511123 @default.
• W1998147949 cites W2025637312 @default.
• W1998147949 cites W2030483725 @default.
• W1998147949 cites W2031101928 @default.
• W1998147949 cites W2031643992 @default.
• W1998147949 cites W2033200028 @default.
• W1998147949 cites W2055073544 @default.
• W1998147949 cites W2056117721 @default.
• W1998147949 cites W2058562215 @default.
• W1998147949 cites W2062830458 @default.
• W1998147949 cites W2068742057 @default.
• W1998147949 cites W2069190224 @default.
• W1998147949 cites W2074460102 @default.
• W1998147949 cites W2079365570 @default.
• W1998147949 cites W2087020488 @default.
• W1998147949 cites W2087685262 @default.
• W1998147949 cites W2087730665 @default.
• W1998147949 cites W2090793677 @default.
• W1998147949 cites W2091372273 @default.
• W1998147949 cites W2091487897 @default.
• W1998147949 cites W2091951560 @default.
• W1998147949 cites W2095751605 @default.
• W1998147949 cites W2112640823 @default.
• W1998147949 cites W2116795024 @default.
• W1998147949 cites W2121127876 @default.
• W1998147949 cites W2134268640 @default.
• W1998147949 cites W2160263002 @default.
• W1998147949 cites W2161886949 @default.
• W1998147949 cites W4292856464 @default.
• W1998147949 cites W4319293053 @default.
• W1998147949 doi "https://doi.org/10.1016/s0091-3057(02)00735-9" @default.
• W1998147949 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12175462" @default.
• W1998147949 hasPublicationYear "2002" @default.
• W1998147949 type Work @default.
• W1998147949 sameAs 1998147949 @default.
• W1998147949 citedByCount "67" @default.
• W1998147949 countsByYear W19981479492012 @default.
• W1998147949 countsByYear W19981479492013 @default.
• W1998147949 countsByYear W19981479492014 @default.
• W1998147949 countsByYear W19981479492015 @default.
• W1998147949 countsByYear W19981479492016 @default.
• W1998147949 countsByYear W19981479492021 @default.
• W1998147949 countsByYear W19981479492022 @default.
• W1998147949 countsByYear W19981479492023 @default.
• W1998147949 crossrefType "journal-article" @default.
• W1998147949 hasAuthorship W1998147949A5006357330 @default.
• W1998147949 hasAuthorship W1998147949A5026011651 @default.
• W1998147949 hasConcept C118552586 @default.
• W1998147949 hasConcept C15744967 @default.
• W1998147949 hasConcept C169760540 @default.
• W1998147949 hasConcept C2776217527 @default.
• W1998147949 hasConcept C2777112843 @default.
• W1998147949 hasConcept C2778555786 @default.
• W1998147949 hasConcept C2780035454 @default.
• W1998147949 hasConcept C2780783007 @default.
• W1998147949 hasConcept C2910455596 @default.
• W1998147949 hasConcept C3018251022 @default.
• W1998147949 hasConcept C42219234 @default.
• W1998147949 hasConcept C71924100 @default.
• W1998147949 hasConcept C98274493 @default.
• W1998147949 hasConceptScore W1998147949C118552586 @default.
• W1998147949 hasConceptScore W1998147949C15744967 @default.
• W1998147949 hasConceptScore W1998147949C169760540 @default.
• W1998147949 hasConceptScore W1998147949C2776217527 @default.
• W1998147949 hasConceptScore W1998147949C2777112843 @default.
• W1998147949 hasConceptScore W1998147949C2778555786 @default.
• W1998147949 hasConceptScore W1998147949C2780035454 @default.
• W1998147949 hasConceptScore W1998147949C2780783007 @default.
• W1998147949 hasConceptScore W1998147949C2910455596 @default.
• W1998147949 hasConceptScore W1998147949C3018251022 @default.
• W1998147949 hasConceptScore W1998147949C42219234 @default.
• W1998147949 hasConceptScore W1998147949C71924100 @default.
• W1998147949 hasConceptScore W1998147949C98274493 @default.
• W1998147949 hasIssue "3" @default.
• W1998147949 hasLocation W19981479491 @default.
• W1998147949 hasLocation W19981479492 @default.
• W1998147949 hasOpenAccess W1998147949 @default.
• W1998147949 hasPrimaryLocation W19981479491 @default.
• W1998147949 hasRelatedWork W104046075 @default.
• W1998147949 hasRelatedWork W1964751335 @default.
• W1998147949 hasRelatedWork W1998147949 @default.

• next