Matches in SemOpenAlex for { <https://semopenalex.org/work/W1998182012> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W1998182012 endingPage "1280" @default.
- W1998182012 startingPage "1276" @default.
- W1998182012 abstract "Intracarotid 1,3-bis(2-chloroethyl)-1-nitrosurea (BCNU) is now a frequently used chemotherapeutic agent for high-grade glial neoplasms. The toxicity from such therapy has not been well-documented. A 50-year-old man with a left frontoparietal grade 4 astrocytoma received three injections of intracarotid BCNU, 400 mg each, over a 2-month period. No radiation or other chemotherapy was ever given. He tolerated the BCNU injections well, with some reduction of tumor bulk, until the third dose. After his last injection, his condition gradually deteriorated; he became obtunded, and died 5 weeks later. At autopsy, the brain showed extensive cavitation and coagulative necrosis, fibrinoid vascular necrosis, edema, swollen axons, and bizarre cellular morphologic features confined to the BCNU perfusion territory. Grade 4 astrocytoma remained in the right hemisphere and in the left occipital lobe, sites outside the area of BCNU perfusion. Intracarotid BCNU can result in a severe leukoencephalopathy similar to that seen with methotrexate or delayed radionecrosis." @default.
- W1998182012 created "2016-06-24" @default.
- W1998182012 creator A5090555830 @default.
- W1998182012 date "1986-04-01" @default.
- W1998182012 modified "2023-10-17" @default.
- W1998182012 title "Intracarotid BCNU leukoencephalopathy" @default.
- W1998182012 cites W1967778414 @default.
- W1998182012 cites W1985741351 @default.
- W1998182012 cites W2011457846 @default.
- W1998182012 cites W2032517241 @default.
- W1998182012 cites W2039452287 @default.
- W1998182012 cites W2048940833 @default.
- W1998182012 cites W2067078624 @default.
- W1998182012 cites W2067434523 @default.
- W1998182012 doi "https://doi.org/10.1002/1097-0142(19860401)57:7<1276::aid-cncr2820570703>3.0.co;2-0" @default.
- W1998182012 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3948112" @default.
- W1998182012 hasPublicationYear "1986" @default.
- W1998182012 type Work @default.
- W1998182012 sameAs 1998182012 @default.
- W1998182012 citedByCount "42" @default.
- W1998182012 countsByYear W19981820122012 @default.
- W1998182012 countsByYear W19981820122015 @default.
- W1998182012 countsByYear W19981820122018 @default.
- W1998182012 crossrefType "journal-article" @default.
- W1998182012 hasAuthorship W1998182012A5090555830 @default.
- W1998182012 hasBestOaLocation W19981820121 @default.
- W1998182012 hasConcept C126838900 @default.
- W1998182012 hasConcept C141071460 @default.
- W1998182012 hasConcept C142724271 @default.
- W1998182012 hasConcept C143409427 @default.
- W1998182012 hasConcept C146957229 @default.
- W1998182012 hasConcept C21613296 @default.
- W1998182012 hasConcept C2776015282 @default.
- W1998182012 hasConcept C2776694085 @default.
- W1998182012 hasConcept C2776755627 @default.
- W1998182012 hasConcept C2778227246 @default.
- W1998182012 hasConcept C2778583010 @default.
- W1998182012 hasConcept C2778880634 @default.
- W1998182012 hasConcept C2779134260 @default.
- W1998182012 hasConcept C2780147359 @default.
- W1998182012 hasConcept C2780886150 @default.
- W1998182012 hasConcept C2781082648 @default.
- W1998182012 hasConcept C502942594 @default.
- W1998182012 hasConcept C503630168 @default.
- W1998182012 hasConcept C71924100 @default.
- W1998182012 hasConceptScore W1998182012C126838900 @default.
- W1998182012 hasConceptScore W1998182012C141071460 @default.
- W1998182012 hasConceptScore W1998182012C142724271 @default.
- W1998182012 hasConceptScore W1998182012C143409427 @default.
- W1998182012 hasConceptScore W1998182012C146957229 @default.
- W1998182012 hasConceptScore W1998182012C21613296 @default.
- W1998182012 hasConceptScore W1998182012C2776015282 @default.
- W1998182012 hasConceptScore W1998182012C2776694085 @default.
- W1998182012 hasConceptScore W1998182012C2776755627 @default.
- W1998182012 hasConceptScore W1998182012C2778227246 @default.
- W1998182012 hasConceptScore W1998182012C2778583010 @default.
- W1998182012 hasConceptScore W1998182012C2778880634 @default.
- W1998182012 hasConceptScore W1998182012C2779134260 @default.
- W1998182012 hasConceptScore W1998182012C2780147359 @default.
- W1998182012 hasConceptScore W1998182012C2780886150 @default.
- W1998182012 hasConceptScore W1998182012C2781082648 @default.
- W1998182012 hasConceptScore W1998182012C502942594 @default.
- W1998182012 hasConceptScore W1998182012C503630168 @default.
- W1998182012 hasConceptScore W1998182012C71924100 @default.
- W1998182012 hasIssue "7" @default.
- W1998182012 hasLocation W19981820121 @default.
- W1998182012 hasLocation W19981820122 @default.
- W1998182012 hasOpenAccess W1998182012 @default.
- W1998182012 hasPrimaryLocation W19981820121 @default.
- W1998182012 hasRelatedWork W1972089539 @default.
- W1998182012 hasRelatedWork W1998182012 @default.
- W1998182012 hasRelatedWork W2013913866 @default.
- W1998182012 hasRelatedWork W2147264580 @default.
- W1998182012 hasRelatedWork W2159539719 @default.
- W1998182012 hasRelatedWork W2317980552 @default.
- W1998182012 hasRelatedWork W2328426833 @default.
- W1998182012 hasRelatedWork W2350508577 @default.
- W1998182012 hasRelatedWork W333125926 @default.
- W1998182012 hasRelatedWork W4280632145 @default.
- W1998182012 hasVolume "57" @default.
- W1998182012 isParatext "false" @default.
- W1998182012 isRetracted "false" @default.
- W1998182012 magId "1998182012" @default.
- W1998182012 workType "article" @default.