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- W1998187356 abstract "In order to evaluate the efficacy and acceptability of 15(S)-15-methyl-prostaglandin F2α (15-me-PGF2α) for pregnancy termination, we induced 30 abortions with single intra-amniotic injections of 2,5 mg of 15-me-PGF2α and 25 abortions with intra-muscular 15-me-PGF2α administered 200 μg initially and 300 μg every third hour until 30 hrs or abortion. Abortion occurred within 30 hrs in 97 % of cases in the intra-amniotic group, with a mean abortion time of 17,6 hrs and in 80 % in the intramuscular group, with a mean abortion time of 15.0 hrs. Neither parity nor gestational age was significantly related to the abortifacient efficacy of 15-me-PGF2α. No serious complications occurred. Vomiting (83–84 %) and diarrhoea (23–92 %) were the most common complaints. Uterine contractions were more painful if induction was effected with intra-amniotic rather than intramuscular injections. 15-me-PGF2α appears to be an effective and practicable abortifacient which can be used intra-amniotically or intramuscularly according to the ease of amniocentesis." @default.
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- W1998187356 date "1975-09-01" @default.
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- W1998187356 title "Induction of abortion with intra-amniotic or intra-muscular 15(S)-15-methyl-prostaglandin F2α" @default.
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- W1998187356 doi "https://doi.org/10.1016/0090-6980(75)90124-0" @default.
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