FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1998224720> ?p ?o ?g. }

• W1998224720 abstract "This study aimed to explore the association between adenocarcinoma-related morphological and molecular characteristics and EGFR mutations in Chinese lung adenocarcinomas. A total of 139 consecutively resected pulmonary adenocarcinoma patients were screened for EGFR mutations by the amplification refractory mutation system assay. For the resected specimens, histologic subtypes were sub-classified using either the 2004 WHO classification or the 2011 IASLC/ATS/ERS classification. Meanwhile, TITF-1 (thyroid transcription factor 1) and SP-A (surfactant-associated protein A) immunohistochemistry staining was also detected. The results were correlated with EGFR mutations and clinicopathological features mentioned above. Both sub-classification methods reflected differences in frequencies of EGFR mutations in lung adenocarcinoma subtypes. In summary, mixed non-mucinous bronchioloalveolar carcinoma (BAC) or papillary components and papillary predominant adenocarcinoma showed a higher frequency of EGFR mutations than mucinous BAC components; Also, EGFR mutations were significantly more common in tumors with TITF-1 or SP-A expressions than in those without (p=0.002, p=0.026), especially the sensitivity of TITF-1 (96.9%) and the negative predictive value of TITF-1 (88.2%). Our data further showed significant genotype-phenotype correlations between EGFR mutations and adenocarcinoma-related morphological and molecular characteristics, and patients with special histologic and IHC staining features might have higher EGFR mutation rates. In addition, this study, for the first time, indicated the significant relationship between SPA IHC and EGFR mutations, which needed confirmation by further research." @default.
• W1998224720 created "2016-06-24" @default.
• W1998224720 creator A5006999345 @default.
• W1998224720 creator A5022202296 @default.
• W1998224720 creator A5030084084 @default.
• W1998224720 creator A5048662409 @default.
• W1998224720 creator A5049277287 @default.
• W1998224720 creator A5054706112 @default.
• W1998224720 creator A5056769236 @default.
• W1998224720 creator A5074149482 @default.
• W1998224720 date "2014-03-01" @default.
• W1998224720 modified "2023-10-16" @default.
• W1998224720 title "Genotype–phenotype correlation in Chinese patients with pulmonary mixed type adenocarcinoma: Relationship between histologic subtypes, TITF-1/SP-A expressions and EGFR mutations" @default.
• W1998224720 cites W1565276921 @default.
• W1998224720 cites W1984094918 @default.
• W1998224720 cites W1986240971 @default.
• W1998224720 cites W1992184657 @default.
• W1998224720 cites W2000714871 @default.
• W1998224720 cites W2028680169 @default.
• W1998224720 cites W2032960138 @default.
• W1998224720 cites W2043966026 @default.
• W1998224720 cites W2045799337 @default.
• W1998224720 cites W2046317081 @default.
• W1998224720 cites W2046956058 @default.
• W1998224720 cites W2054948285 @default.
• W1998224720 cites W2056625156 @default.
• W1998224720 cites W2063310038 @default.
• W1998224720 cites W2064063117 @default.
• W1998224720 cites W2076734146 @default.
• W1998224720 cites W2084756787 @default.
• W1998224720 cites W2095635764 @default.
• W1998224720 cites W2095673635 @default.
• W1998224720 cites W2105626660 @default.
• W1998224720 cites W2111710483 @default.
• W1998224720 cites W2118019849 @default.
• W1998224720 cites W2129802084 @default.
• W1998224720 cites W2130419731 @default.
• W1998224720 cites W2132000016 @default.
• W1998224720 cites W2161042246 @default.
• W1998224720 cites W2162705771 @default.
• W1998224720 cites W2163049570 @default.
• W1998224720 cites W2166084034 @default.
• W1998224720 cites W2166351918 @default.
• W1998224720 cites W4328001267 @default.
• W1998224720 doi "https://doi.org/10.1016/j.prp.2013.11.013" @default.
• W1998224720 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24370340" @default.
• W1998224720 hasPublicationYear "2014" @default.
• W1998224720 type Work @default.
• W1998224720 sameAs 1998224720 @default.
• W1998224720 citedByCount "18" @default.
• W1998224720 countsByYear W19982247202014 @default.
• W1998224720 countsByYear W19982247202015 @default.
• W1998224720 countsByYear W19982247202016 @default.
• W1998224720 countsByYear W19982247202017 @default.
• W1998224720 countsByYear W19982247202019 @default.
• W1998224720 countsByYear W19982247202020 @default.
• W1998224720 countsByYear W19982247202021 @default.
• W1998224720 countsByYear W19982247202022 @default.
• W1998224720 crossrefType "journal-article" @default.
• W1998224720 hasAuthorship W1998224720A5006999345 @default.
• W1998224720 hasAuthorship W1998224720A5022202296 @default.
• W1998224720 hasAuthorship W1998224720A5030084084 @default.
• W1998224720 hasAuthorship W1998224720A5048662409 @default.
• W1998224720 hasAuthorship W1998224720A5049277287 @default.
• W1998224720 hasAuthorship W1998224720A5054706112 @default.
• W1998224720 hasAuthorship W1998224720A5056769236 @default.
• W1998224720 hasAuthorship W1998224720A5074149482 @default.
• W1998224720 hasConcept C104317684 @default.
• W1998224720 hasConcept C121608353 @default.
• W1998224720 hasConcept C126322002 @default.
• W1998224720 hasConcept C127716648 @default.
• W1998224720 hasConcept C135763542 @default.
• W1998224720 hasConcept C142724271 @default.
• W1998224720 hasConcept C204232928 @default.
• W1998224720 hasConcept C2776256026 @default.
• W1998224720 hasConcept C2777546739 @default.
• W1998224720 hasConcept C2781182431 @default.
• W1998224720 hasConcept C2909723608 @default.
• W1998224720 hasConcept C2909744358 @default.
• W1998224720 hasConcept C501734568 @default.
• W1998224720 hasConcept C502942594 @default.
• W1998224720 hasConcept C54355233 @default.
• W1998224720 hasConcept C57742111 @default.
• W1998224720 hasConcept C71924100 @default.
• W1998224720 hasConcept C86803240 @default.
• W1998224720 hasConceptScore W1998224720C104317684 @default.
• W1998224720 hasConceptScore W1998224720C121608353 @default.
• W1998224720 hasConceptScore W1998224720C126322002 @default.
• W1998224720 hasConceptScore W1998224720C127716648 @default.
• W1998224720 hasConceptScore W1998224720C135763542 @default.
• W1998224720 hasConceptScore W1998224720C142724271 @default.
• W1998224720 hasConceptScore W1998224720C204232928 @default.
• W1998224720 hasConceptScore W1998224720C2776256026 @default.
• W1998224720 hasConceptScore W1998224720C2777546739 @default.
• W1998224720 hasConceptScore W1998224720C2781182431 @default.
• W1998224720 hasConceptScore W1998224720C2909723608 @default.
• W1998224720 hasConceptScore W1998224720C2909744358 @default.
• W1998224720 hasConceptScore W1998224720C501734568 @default.
• W1998224720 hasConceptScore W1998224720C502942594 @default.
• W1998224720 hasConceptScore W1998224720C54355233 @default.

• next