Matches in SemOpenAlex for { <https://semopenalex.org/work/W1998254021> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W1998254021 endingPage "824" @default.
- W1998254021 startingPage "820" @default.
- W1998254021 abstract "The pubertal maturation of five boys (Group A) who were initially thought to be gonadotropin deficient was studied over 10 to 58 months (mean 36 months) by serial physical examinatons and standard GnRH tests. Four were seen because of obesity, delayed sexual maturation, depression, and poor school performance. The other boy had acquired hypothalamic hypopituitarism at 13 years of age. Gonadotropin responses during the initial GnRH test were either absent or abnormally low as related to the degree of skeletal maturation. Subsequent responses showed progressive maturation into the normal range for adult males. These boys had normal olfaction and moderate-to-marked obesity, but initial assessment of testicular size, basal gonadotropins, and testosterone or gonadotropin responses to GnRH did not distinguish these boys from seven patients with isolated gonadotropin deficiency (Group B). Contrary to previous reports and expectations, these studies indicate that an absent or markedly blunted response to synthetic GnRH is not diagnostic of gonadotropin deficiency, even when skeletal age is 12 years or greater. Furthermore, unless a patient is hyposomic or anosmic, or has an associated anomaly such as cleft palate, isolated gonadotropin deficiency cannot be diagnosed reliably until late adolescence or early adulthood." @default.
- W1998254021 created "2016-06-24" @default.
- W1998254021 creator A5020447150 @default.
- W1998254021 creator A5063077154 @default.
- W1998254021 creator A5070604004 @default.
- W1998254021 date "1980-11-01" @default.
- W1998254021 modified "2023-09-25" @default.
- W1998254021 title "Diagnosis of gonadotropin deficiency in adolescents: Limited usefulness of a standard gonadotropin-releasing hormone test in obese boys" @default.
- W1998254021 cites W1964094088 @default.
- W1998254021 cites W1968963285 @default.
- W1998254021 cites W1986826867 @default.
- W1998254021 cites W2003738655 @default.
- W1998254021 cites W2034548451 @default.
- W1998254021 cites W2057293033 @default.
- W1998254021 cites W2070173371 @default.
- W1998254021 cites W2094546920 @default.
- W1998254021 cites W2100100394 @default.
- W1998254021 cites W2107732834 @default.
- W1998254021 cites W2134433172 @default.
- W1998254021 cites W2158892504 @default.
- W1998254021 cites W2169918473 @default.
- W1998254021 doi "https://doi.org/10.1016/s0022-3476(80)80279-4" @default.
- W1998254021 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6776256" @default.
- W1998254021 hasPublicationYear "1980" @default.
- W1998254021 type Work @default.
- W1998254021 sameAs 1998254021 @default.
- W1998254021 citedByCount "35" @default.
- W1998254021 countsByYear W19982540212013 @default.
- W1998254021 countsByYear W19982540212014 @default.
- W1998254021 countsByYear W19982540212020 @default.
- W1998254021 countsByYear W19982540212022 @default.
- W1998254021 crossrefType "journal-article" @default.
- W1998254021 hasAuthorship W1998254021A5020447150 @default.
- W1998254021 hasAuthorship W1998254021A5063077154 @default.
- W1998254021 hasAuthorship W1998254021A5070604004 @default.
- W1998254021 hasConcept C126322002 @default.
- W1998254021 hasConcept C134018914 @default.
- W1998254021 hasConcept C2778024521 @default.
- W1998254021 hasConcept C2778575703 @default.
- W1998254021 hasConcept C2778782382 @default.
- W1998254021 hasConcept C2778894405 @default.
- W1998254021 hasConcept C2779279991 @default.
- W1998254021 hasConcept C2779306644 @default.
- W1998254021 hasConcept C71315377 @default.
- W1998254021 hasConcept C71924100 @default.
- W1998254021 hasConcept C89551170 @default.
- W1998254021 hasConceptScore W1998254021C126322002 @default.
- W1998254021 hasConceptScore W1998254021C134018914 @default.
- W1998254021 hasConceptScore W1998254021C2778024521 @default.
- W1998254021 hasConceptScore W1998254021C2778575703 @default.
- W1998254021 hasConceptScore W1998254021C2778782382 @default.
- W1998254021 hasConceptScore W1998254021C2778894405 @default.
- W1998254021 hasConceptScore W1998254021C2779279991 @default.
- W1998254021 hasConceptScore W1998254021C2779306644 @default.
- W1998254021 hasConceptScore W1998254021C71315377 @default.
- W1998254021 hasConceptScore W1998254021C71924100 @default.
- W1998254021 hasConceptScore W1998254021C89551170 @default.
- W1998254021 hasIssue "5" @default.
- W1998254021 hasLocation W19982540211 @default.
- W1998254021 hasLocation W19982540212 @default.
- W1998254021 hasOpenAccess W1998254021 @default.
- W1998254021 hasPrimaryLocation W19982540211 @default.
- W1998254021 hasRelatedWork W1541445894 @default.
- W1998254021 hasRelatedWork W1968547000 @default.
- W1998254021 hasRelatedWork W1981222718 @default.
- W1998254021 hasRelatedWork W2012502375 @default.
- W1998254021 hasRelatedWork W2025304600 @default.
- W1998254021 hasRelatedWork W2040233599 @default.
- W1998254021 hasRelatedWork W2057000165 @default.
- W1998254021 hasRelatedWork W2067589401 @default.
- W1998254021 hasRelatedWork W2086384643 @default.
- W1998254021 hasRelatedWork W2135456085 @default.
- W1998254021 hasVolume "97" @default.
- W1998254021 isParatext "false" @default.
- W1998254021 isRetracted "false" @default.
- W1998254021 magId "1998254021" @default.
- W1998254021 workType "article" @default.