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- W1998257546 abstract "Five mutations in ccpA of Bacillus megaterium with impaired functions were analysed for carbon catabolite repression. The phenotypes support the hypothesis that CcpA assumes a PurR/LacI fold. The completely inactive mutants CcpA119GE and CcpA326am cause alterations which are incompatible with that fold. A mutation with reduced activity, CcpA81GE, affects a site that would be partially surface exposed and may interfere with structure formation or cofactor binding. A mutation in the putative hinge alpha-helix, CcpA52AE, is negative transdominant over wild-type ccpA. The mutant CcpA38am is inactive, although reduced amounts of wild-type size protein are produced." @default.
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- W1998257546 date "2006-01-17" @default.
- W1998257546 modified "2023-10-16" @default.
- W1998257546 title "Analysis of CcpA mutations defective in carbon catabolite repression in Bacillus megaterium" @default.
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- W1998257546 doi "https://doi.org/10.1111/j.1574-6968.1997.tb10485.x" @default.
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