Matches in SemOpenAlex for { <https://semopenalex.org/work/W1998264906> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W1998264906 endingPage "1769" @default.
- W1998264906 startingPage "1765" @default.
- W1998264906 abstract "We adduce several lines of evidence to indicate that the inhibition of histamine release from rat mast cells by cytochalasin A (Cyto A) depends on its reactivity with mast cell sulfhydryl (SH) groups: (1) Cyto A reacts with cysteine, glutathione and protein SH groups ; (2) prior reaction of Cyto A with glutathione eliminates its inhibitory action; and (3) 2,2'-dithiodipyridine (DTDP), a SH reagent with greater specificity for SH groups and very different structure from Cyto A, has parallel inhibitory effects on mast cell secretion. Inhibition of histamine release by Cyto A or by DTDP is independent of depression of cell ATP or cell glutathione. Inhibition of release induced by the calcium ionophore A23187 and polymyxin suggests that the two SH reagents act to block the release mechanism subsequent to a putative increase in cytoplasmic Ca2+ concentration. In contrast, N(7-dimethylamino-4-methylcoumarinyl)maleimide (DACM), p-chloromercuri-benzene sulfonate (PCMBS) and N-ethylmaleimide (NEM) (< 10−5 M) appear to react with a SH group required for polymyxin B but not A23187-induced release. The effect of NEM at high concentrations (5 × 10−5 M) is attributable to depression of cell ATP." @default.
- W1998264906 created "2016-06-24" @default.
- W1998264906 creator A5040544077 @default.
- W1998264906 creator A5091381778 @default.
- W1998264906 date "1979-06-01" @default.
- W1998264906 modified "2023-10-17" @default.
- W1998264906 title "Inhibition of histamine release from rat mast cells by cytochalasin A and other sulfhydryl reagents" @default.
- W1998264906 cites W1521946047 @default.
- W1998264906 cites W1571493262 @default.
- W1998264906 cites W1577938353 @default.
- W1998264906 cites W1963862229 @default.
- W1998264906 cites W1965693625 @default.
- W1998264906 cites W1988578564 @default.
- W1998264906 cites W2007064404 @default.
- W1998264906 cites W2021947657 @default.
- W1998264906 cites W2029169586 @default.
- W1998264906 cites W2036474910 @default.
- W1998264906 cites W2066099433 @default.
- W1998264906 cites W2068231720 @default.
- W1998264906 cites W2072975222 @default.
- W1998264906 cites W2074086451 @default.
- W1998264906 cites W2106053019 @default.
- W1998264906 cites W2199171951 @default.
- W1998264906 cites W578740912 @default.
- W1998264906 cites W2094629448 @default.
- W1998264906 doi "https://doi.org/10.1016/0006-2952(79)90538-0" @default.
- W1998264906 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/89848" @default.
- W1998264906 hasPublicationYear "1979" @default.
- W1998264906 type Work @default.
- W1998264906 sameAs 1998264906 @default.
- W1998264906 citedByCount "19" @default.
- W1998264906 crossrefType "journal-article" @default.
- W1998264906 hasAuthorship W1998264906A5040544077 @default.
- W1998264906 hasAuthorship W1998264906A5091381778 @default.
- W1998264906 hasConcept C1122143 @default.
- W1998264906 hasConcept C142669718 @default.
- W1998264906 hasConcept C1491633281 @default.
- W1998264906 hasConcept C153911025 @default.
- W1998264906 hasConcept C178790620 @default.
- W1998264906 hasConcept C181199279 @default.
- W1998264906 hasConcept C185592680 @default.
- W1998264906 hasConcept C203014093 @default.
- W1998264906 hasConcept C2775995422 @default.
- W1998264906 hasConcept C2776515853 @default.
- W1998264906 hasConcept C2779012151 @default.
- W1998264906 hasConcept C2779201268 @default.
- W1998264906 hasConcept C2779726688 @default.
- W1998264906 hasConcept C519063684 @default.
- W1998264906 hasConcept C538909803 @default.
- W1998264906 hasConcept C55493867 @default.
- W1998264906 hasConcept C86803240 @default.
- W1998264906 hasConcept C98274493 @default.
- W1998264906 hasConceptScore W1998264906C1122143 @default.
- W1998264906 hasConceptScore W1998264906C142669718 @default.
- W1998264906 hasConceptScore W1998264906C1491633281 @default.
- W1998264906 hasConceptScore W1998264906C153911025 @default.
- W1998264906 hasConceptScore W1998264906C178790620 @default.
- W1998264906 hasConceptScore W1998264906C181199279 @default.
- W1998264906 hasConceptScore W1998264906C185592680 @default.
- W1998264906 hasConceptScore W1998264906C203014093 @default.
- W1998264906 hasConceptScore W1998264906C2775995422 @default.
- W1998264906 hasConceptScore W1998264906C2776515853 @default.
- W1998264906 hasConceptScore W1998264906C2779012151 @default.
- W1998264906 hasConceptScore W1998264906C2779201268 @default.
- W1998264906 hasConceptScore W1998264906C2779726688 @default.
- W1998264906 hasConceptScore W1998264906C519063684 @default.
- W1998264906 hasConceptScore W1998264906C538909803 @default.
- W1998264906 hasConceptScore W1998264906C55493867 @default.
- W1998264906 hasConceptScore W1998264906C86803240 @default.
- W1998264906 hasConceptScore W1998264906C98274493 @default.
- W1998264906 hasIssue "11" @default.
- W1998264906 hasLocation W19982649061 @default.
- W1998264906 hasLocation W19982649062 @default.
- W1998264906 hasOpenAccess W1998264906 @default.
- W1998264906 hasPrimaryLocation W19982649061 @default.
- W1998264906 hasRelatedWork W1581167643 @default.
- W1998264906 hasRelatedWork W1981515610 @default.
- W1998264906 hasRelatedWork W1983972257 @default.
- W1998264906 hasRelatedWork W1992468053 @default.
- W1998264906 hasRelatedWork W1998264906 @default.
- W1998264906 hasRelatedWork W2020952609 @default.
- W1998264906 hasRelatedWork W2041383307 @default.
- W1998264906 hasRelatedWork W2077655969 @default.
- W1998264906 hasRelatedWork W2338209583 @default.
- W1998264906 hasRelatedWork W2415814120 @default.
- W1998264906 hasVolume "28" @default.
- W1998264906 isParatext "false" @default.
- W1998264906 isRetracted "false" @default.
- W1998264906 magId "1998264906" @default.
- W1998264906 workType "article" @default.