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- W1998267966 abstract "This study shows that topoisomerase II and MutS proteins share a structural motif that has, in its dimeric form, a suitable geometry for clamping the two arms of either right-handed DNA crossovers or their isostructural stacked Holliday junctions. This defines a new protein family selected by convergent evolution for sensing DNA topology and binding recombination intermediates. This study also proposes that MutS binding on 2-fold right-handed crossover provides a mechanism for strand discrimination during DNA translocation." @default.
- W1998267966 created "2016-06-24" @default.
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- W1998267966 date "2001-10-01" @default.
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- W1998267966 title "Convergent Evolution of MutS and Topoisomerase II for Clamping DNA crossovers and stacked Holliday junctions" @default.
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- W1998267966 doi "https://doi.org/10.1080/07391102.2001.10506733" @default.
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