Matches in SemOpenAlex for { <https://semopenalex.org/work/W1998286557> ?p ?o ?g. }
- W1998286557 endingPage "229" @default.
- W1998286557 startingPage "229" @default.
- W1998286557 abstract "Update on the rational use of tositumomab and iodine-131 tositumomab radioimmunotherapy for the treatment of non-Hodgkin’s lymphoma Michael J Burdick, Roger M MacklisDepartment of Radiation Oncology, Taussig Cancer Center and Cleveland Clinic Lerner College of Medicine, Cleveland, OH, USAAbstract: Targeted radioimmunotherapy in non-Hodgkin’s B-cell lymphoma (NHL) offers an efficacious therapy and minimal toxicity compared to conventional chemotherapy. Iodine 131 tositumomab (131I-TST) is a murine monoclonal antibody against the CD20 cell surface protein and is directly covalently conjugated to 131I, a radioactive β and γ emitter. While initially approved for use in relapsed, refractory, or transformed low grade B-cell NHL, investigational uses with promising results include autologous stem cell transplant, intermediate grade NHL, and the frontline management of indolent NHL. This review summarizes the 131I-TST literature on mechanism of action, treatment indications, treatment delivery, efficacy, investigational uses, and future prospects.Keywords: tositumomab, radioimmunotherapy, non-Hodgkin’s lymphoma, Bexxar" @default.
- W1998286557 created "2016-06-24" @default.
- W1998286557 creator A5033875429 @default.
- W1998286557 creator A5080250378 @default.
- W1998286557 date "2009-08-01" @default.
- W1998286557 modified "2023-09-30" @default.
- W1998286557 title "Update on the rational use of tositumomab and iodine-131 tositumomab radioimmunotherapy for the treatment of non-Hodgkin’s lymphoma" @default.
- W1998286557 cites W147398146 @default.
- W1998286557 cites W1573890015 @default.
- W1998286557 cites W1892026381 @default.
- W1998286557 cites W1893837372 @default.
- W1998286557 cites W1915689252 @default.
- W1998286557 cites W1923038941 @default.
- W1998286557 cites W1933173754 @default.
- W1998286557 cites W1967417752 @default.
- W1998286557 cites W1994649805 @default.
- W1998286557 cites W2014654561 @default.
- W1998286557 cites W2020764618 @default.
- W1998286557 cites W2024451191 @default.
- W1998286557 cites W2027374210 @default.
- W1998286557 cites W2043103956 @default.
- W1998286557 cites W2044360617 @default.
- W1998286557 cites W2048260069 @default.
- W1998286557 cites W2058015212 @default.
- W1998286557 cites W2061803727 @default.
- W1998286557 cites W2063708816 @default.
- W1998286557 cites W2063792914 @default.
- W1998286557 cites W206701898 @default.
- W1998286557 cites W2075141373 @default.
- W1998286557 cites W2075785757 @default.
- W1998286557 cites W2084493022 @default.
- W1998286557 cites W2089298737 @default.
- W1998286557 cites W2092101307 @default.
- W1998286557 cites W2092848033 @default.
- W1998286557 cites W2103929387 @default.
- W1998286557 cites W2111591374 @default.
- W1998286557 cites W2118334991 @default.
- W1998286557 cites W2119098512 @default.
- W1998286557 cites W2123185965 @default.
- W1998286557 cites W2124011708 @default.
- W1998286557 cites W2126539571 @default.
- W1998286557 cites W2128997140 @default.
- W1998286557 cites W2132128887 @default.
- W1998286557 cites W2133201432 @default.
- W1998286557 cites W2134090290 @default.
- W1998286557 cites W2134342060 @default.
- W1998286557 cites W2135157531 @default.
- W1998286557 cites W2150966373 @default.
- W1998286557 cites W2152526200 @default.
- W1998286557 cites W2152911354 @default.
- W1998286557 cites W2160885679 @default.
- W1998286557 cites W2168188707 @default.
- W1998286557 cites W2256269697 @default.
- W1998286557 cites W2256690185 @default.
- W1998286557 cites W2312437021 @default.
- W1998286557 cites W2314426561 @default.
- W1998286557 cites W2320751441 @default.
- W1998286557 cites W2411735017 @default.
- W1998286557 cites W2604669391 @default.
- W1998286557 cites W1603051829 @default.
- W1998286557 doi "https://doi.org/10.2147/ott.s4456" @default.
- W1998286557 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2886324" @default.
- W1998286557 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20616910" @default.
- W1998286557 hasPublicationYear "2009" @default.
- W1998286557 type Work @default.
- W1998286557 sameAs 1998286557 @default.
- W1998286557 citedByCount "4" @default.
- W1998286557 countsByYear W19982865572016 @default.
- W1998286557 countsByYear W19982865572017 @default.
- W1998286557 crossrefType "journal-article" @default.
- W1998286557 hasAuthorship W1998286557A5033875429 @default.
- W1998286557 hasAuthorship W1998286557A5080250378 @default.
- W1998286557 hasBestOaLocation W19982865571 @default.
- W1998286557 hasConcept C126322002 @default.
- W1998286557 hasConcept C143998085 @default.
- W1998286557 hasConcept C159654299 @default.
- W1998286557 hasConcept C203014093 @default.
- W1998286557 hasConcept C2776146153 @default.
- W1998286557 hasConcept C2778515704 @default.
- W1998286557 hasConcept C2779338263 @default.
- W1998286557 hasConcept C502942594 @default.
- W1998286557 hasConcept C542903549 @default.
- W1998286557 hasConcept C71924100 @default.
- W1998286557 hasConceptScore W1998286557C126322002 @default.
- W1998286557 hasConceptScore W1998286557C143998085 @default.
- W1998286557 hasConceptScore W1998286557C159654299 @default.
- W1998286557 hasConceptScore W1998286557C203014093 @default.
- W1998286557 hasConceptScore W1998286557C2776146153 @default.
- W1998286557 hasConceptScore W1998286557C2778515704 @default.
- W1998286557 hasConceptScore W1998286557C2779338263 @default.
- W1998286557 hasConceptScore W1998286557C502942594 @default.
- W1998286557 hasConceptScore W1998286557C542903549 @default.
- W1998286557 hasConceptScore W1998286557C71924100 @default.
- W1998286557 hasLocation W19982865571 @default.
- W1998286557 hasLocation W19982865572 @default.
- W1998286557 hasLocation W19982865573 @default.
- W1998286557 hasLocation W19982865574 @default.
- W1998286557 hasOpenAccess W1998286557 @default.