Matches in SemOpenAlex for { <https://semopenalex.org/work/W1998289531> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W1998289531 endingPage "1566" @default.
- W1998289531 startingPage "1559" @default.
- W1998289531 abstract "Fructose intake has increased considerably in the United States, primarily as a result of increased consumption of high-fructose corn syrup, fruits and juices, and crystalline fructose. The purpose was to determine how often fructose, in amounts commonly consumed, would result in malabsorption and/or symptoms in healthy persons.Fructose absorption was measured using 3-hour breath hydrogen tests and symptom scores were used to rate subjective responses for gas, borborygmus, abdominal pain, and loose stools.The study included 15 normal, free-living volunteers from a medical center community and was performed in a gastrointestinal specialty clinic.Subjects consumed 25- and 50-g doses of crystalline fructose with water after an overnight fast on separate test days.Mean peak breath hydrogen, time of peak, area under the curve (AUC) for breath hydrogen and gastrointestinal symptoms were measured during a 3-hour period after subjects consumed both 25- and 50-g doses of fructose.Differences in mean breath hydrogen, AUC, and symptom scores between doses were analyzed using paired t tests. Correlations among peak breath hydrogen, AUC, and symptoms were also evaluated.More than half of the 15 adults tested showed evidence of fructose malabsorption after 25 g fructose and greater than two thirds showed malabsorption after 50 g fructose. AUC, representing overall breath hydrogen response, was significantly greater after the 50-g dose. Overall symptom scores were significantly greater than baseline after each dose, but scores were only marginally greater after 50 g than 25 g. Peak hydrogen levels and AUC were highly correlated, but neither was significantly related to symptoms.Fructose, in amounts commonly consumed, may result in mild gastrointestinal distress in normal people. Additional study is warranted to evaluate the response to fructose-glucose mixtures (as in high-fructose corn syrup) and fructose taken with food in both normal people and those with gastrointestinal dysfunction. Because breath hydrogen peaks occurred at 90 to 114 minutes and were highly correlated with 180-minute breath hydrogen AUC, the use of peak hydrogen measures may be considered to shorten the duration of the exam." @default.
- W1998289531 created "2016-06-24" @default.
- W1998289531 creator A5005028574 @default.
- W1998289531 creator A5064847840 @default.
- W1998289531 creator A5087742173 @default.
- W1998289531 date "2005-10-01" @default.
- W1998289531 modified "2023-09-24" @default.
- W1998289531 title "Fructose Intake at Current Levels in the United States May Cause Gastrointestinal Distress in Normal Adults" @default.
- W1998289531 cites W1491501503 @default.
- W1998289531 cites W1513349500 @default.
- W1998289531 cites W1532908502 @default.
- W1998289531 cites W1907660814 @default.
- W1998289531 cites W1918209772 @default.
- W1998289531 cites W1921836405 @default.
- W1998289531 cites W1949482878 @default.
- W1998289531 cites W1967799528 @default.
- W1998289531 cites W1975166496 @default.
- W1998289531 cites W1987760731 @default.
- W1998289531 cites W2025787160 @default.
- W1998289531 cites W2033573730 @default.
- W1998289531 cites W2040449437 @default.
- W1998289531 cites W2045561699 @default.
- W1998289531 cites W2081142242 @default.
- W1998289531 cites W2090521573 @default.
- W1998289531 cites W2106031890 @default.
- W1998289531 cites W2130578257 @default.
- W1998289531 cites W2135766400 @default.
- W1998289531 cites W2138903264 @default.
- W1998289531 cites W2153074524 @default.
- W1998289531 cites W2333490207 @default.
- W1998289531 cites W4235992096 @default.
- W1998289531 doi "https://doi.org/10.1016/j.jada.2005.07.002" @default.
- W1998289531 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16183355" @default.
- W1998289531 hasPublicationYear "2005" @default.
- W1998289531 type Work @default.
- W1998289531 sameAs 1998289531 @default.
- W1998289531 citedByCount "79" @default.
- W1998289531 countsByYear W19982895312012 @default.
- W1998289531 countsByYear W19982895312013 @default.
- W1998289531 countsByYear W19982895312014 @default.
- W1998289531 countsByYear W19982895312015 @default.
- W1998289531 countsByYear W19982895312016 @default.
- W1998289531 countsByYear W19982895312017 @default.
- W1998289531 countsByYear W19982895312018 @default.
- W1998289531 countsByYear W19982895312019 @default.
- W1998289531 countsByYear W19982895312020 @default.
- W1998289531 countsByYear W19982895312021 @default.
- W1998289531 countsByYear W19982895312022 @default.
- W1998289531 countsByYear W19982895312023 @default.
- W1998289531 crossrefType "journal-article" @default.
- W1998289531 hasAuthorship W1998289531A5005028574 @default.
- W1998289531 hasAuthorship W1998289531A5064847840 @default.
- W1998289531 hasAuthorship W1998289531A5087742173 @default.
- W1998289531 hasConcept C126322002 @default.
- W1998289531 hasConcept C134018914 @default.
- W1998289531 hasConcept C185592680 @default.
- W1998289531 hasConcept C2775981797 @default.
- W1998289531 hasConcept C2776409635 @default.
- W1998289531 hasConcept C2776970464 @default.
- W1998289531 hasConcept C2780439177 @default.
- W1998289531 hasConcept C31903555 @default.
- W1998289531 hasConcept C71924100 @default.
- W1998289531 hasConcept C76318530 @default.
- W1998289531 hasConcept C90924648 @default.
- W1998289531 hasConceptScore W1998289531C126322002 @default.
- W1998289531 hasConceptScore W1998289531C134018914 @default.
- W1998289531 hasConceptScore W1998289531C185592680 @default.
- W1998289531 hasConceptScore W1998289531C2775981797 @default.
- W1998289531 hasConceptScore W1998289531C2776409635 @default.
- W1998289531 hasConceptScore W1998289531C2776970464 @default.
- W1998289531 hasConceptScore W1998289531C2780439177 @default.
- W1998289531 hasConceptScore W1998289531C31903555 @default.
- W1998289531 hasConceptScore W1998289531C71924100 @default.
- W1998289531 hasConceptScore W1998289531C76318530 @default.
- W1998289531 hasConceptScore W1998289531C90924648 @default.
- W1998289531 hasIssue "10" @default.
- W1998289531 hasLocation W19982895311 @default.
- W1998289531 hasLocation W19982895312 @default.
- W1998289531 hasOpenAccess W1998289531 @default.
- W1998289531 hasPrimaryLocation W19982895311 @default.
- W1998289531 hasRelatedWork W1898816935 @default.
- W1998289531 hasRelatedWork W2028937980 @default.
- W1998289531 hasRelatedWork W2084269377 @default.
- W1998289531 hasRelatedWork W2153170362 @default.
- W1998289531 hasRelatedWork W2317656387 @default.
- W1998289531 hasRelatedWork W2330099783 @default.
- W1998289531 hasRelatedWork W2767486483 @default.
- W1998289531 hasRelatedWork W2890099229 @default.
- W1998289531 hasRelatedWork W2894554387 @default.
- W1998289531 hasRelatedWork W2425704862 @default.
- W1998289531 hasVolume "105" @default.
- W1998289531 isParatext "false" @default.
- W1998289531 isRetracted "false" @default.
- W1998289531 magId "1998289531" @default.
- W1998289531 workType "article" @default.