Matches in SemOpenAlex for { <https://semopenalex.org/work/W1998293863> ?p ?o ?g. }
- W1998293863 endingPage "160" @default.
- W1998293863 startingPage "155" @default.
- W1998293863 abstract "The effect of chloride ion on transport of [3H]dopamine into synaptic vesicles purified from rat striatum has been evaluated. The inclusion of 10 mM chloride ion in the incubation medium produced a 100% increase in temperature-sensitive [3H]dopamine uptake into synaptic vesicles from approximately 1800 pmol/mg to 3600 pmol/mg of protein. Half-maximal effects were observed with chloride ion at 4 mM concentration. The anion selectivity of stimulation supports the presence of anion channels within the membranes of dopaminergic storage organelles. Low concentrations of thiocyanate ion (<10 mM), 4-acetamido-4′-isothiocyano2-2′-disulfonic acid stilbene (100 μM), and duramycin (5 μg/ml) selectively blocked the chloride ion stimulated accumulation of [3H]dopamine. Higher concentrations of these agents are required to significantly reduce [3H]dopamine uptake in the absence of chloride ion. These results suggest that both components of the proton electrochemical gradient (ΔΨ and δpH) are important for dopamine uptake by brain vesicles. This article presents the first demonstration that chloride ion plays a role in the transport of dopamine into vesicles isolated from the CNS." @default.
- W1998293863 created "2016-06-24" @default.
- W1998293863 creator A5018273854 @default.
- W1998293863 creator A5039253288 @default.
- W1998293863 creator A5051357303 @default.
- W1998293863 creator A5058701097 @default.
- W1998293863 creator A5059047598 @default.
- W1998293863 date "1990-05-01" @default.
- W1998293863 modified "2023-10-16" @default.
- W1998293863 title "Chloride ion increases [3H]dopamine accumulation by synaptic vesicles purified from rat striatum: inhibition by thiocyanate ion" @default.
- W1998293863 cites W1488933314 @default.
- W1998293863 cites W1525322176 @default.
- W1998293863 cites W1541602774 @default.
- W1998293863 cites W1541990150 @default.
- W1998293863 cites W1547792612 @default.
- W1998293863 cites W155580700 @default.
- W1998293863 cites W1671926542 @default.
- W1998293863 cites W190883241 @default.
- W1998293863 cites W1976474622 @default.
- W1998293863 cites W1980428287 @default.
- W1998293863 cites W1992367492 @default.
- W1998293863 cites W1996691551 @default.
- W1998293863 cites W2006290783 @default.
- W1998293863 cites W2028384673 @default.
- W1998293863 cites W2029192836 @default.
- W1998293863 cites W2037067309 @default.
- W1998293863 cites W2041996552 @default.
- W1998293863 cites W2044696207 @default.
- W1998293863 cites W2049192908 @default.
- W1998293863 cites W2056601607 @default.
- W1998293863 cites W2058939537 @default.
- W1998293863 cites W2065063347 @default.
- W1998293863 cites W2080107080 @default.
- W1998293863 cites W2084523150 @default.
- W1998293863 cites W2084741371 @default.
- W1998293863 cites W2087552293 @default.
- W1998293863 cites W2136345386 @default.
- W1998293863 cites W2158402600 @default.
- W1998293863 cites W2233259413 @default.
- W1998293863 cites W2233325002 @default.
- W1998293863 cites W4231780504 @default.
- W1998293863 cites W4251474007 @default.
- W1998293863 cites W4293247451 @default.
- W1998293863 doi "https://doi.org/10.1016/0006-8993(90)90912-u" @default.
- W1998293863 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1694707" @default.
- W1998293863 hasPublicationYear "1990" @default.
- W1998293863 type Work @default.
- W1998293863 sameAs 1998293863 @default.
- W1998293863 citedByCount "33" @default.
- W1998293863 countsByYear W19982938632012 @default.
- W1998293863 countsByYear W19982938632013 @default.
- W1998293863 countsByYear W19982938632014 @default.
- W1998293863 countsByYear W19982938632015 @default.
- W1998293863 countsByYear W19982938632017 @default.
- W1998293863 countsByYear W19982938632019 @default.
- W1998293863 countsByYear W19982938632020 @default.
- W1998293863 crossrefType "journal-article" @default.
- W1998293863 hasAuthorship W1998293863A5018273854 @default.
- W1998293863 hasAuthorship W1998293863A5039253288 @default.
- W1998293863 hasAuthorship W1998293863A5051357303 @default.
- W1998293863 hasAuthorship W1998293863A5058701097 @default.
- W1998293863 hasAuthorship W1998293863A5059047598 @default.
- W1998293863 hasConcept C12554922 @default.
- W1998293863 hasConcept C130316041 @default.
- W1998293863 hasConcept C134018914 @default.
- W1998293863 hasConcept C137183658 @default.
- W1998293863 hasConcept C148785051 @default.
- W1998293863 hasConcept C178790620 @default.
- W1998293863 hasConcept C185592680 @default.
- W1998293863 hasConcept C2776294642 @default.
- W1998293863 hasConcept C2776755682 @default.
- W1998293863 hasConcept C2778695967 @default.
- W1998293863 hasConcept C2780062018 @default.
- W1998293863 hasConcept C41625074 @default.
- W1998293863 hasConcept C513476851 @default.
- W1998293863 hasConcept C55493867 @default.
- W1998293863 hasConcept C86803240 @default.
- W1998293863 hasConcept C99975950 @default.
- W1998293863 hasConceptScore W1998293863C12554922 @default.
- W1998293863 hasConceptScore W1998293863C130316041 @default.
- W1998293863 hasConceptScore W1998293863C134018914 @default.
- W1998293863 hasConceptScore W1998293863C137183658 @default.
- W1998293863 hasConceptScore W1998293863C148785051 @default.
- W1998293863 hasConceptScore W1998293863C178790620 @default.
- W1998293863 hasConceptScore W1998293863C185592680 @default.
- W1998293863 hasConceptScore W1998293863C2776294642 @default.
- W1998293863 hasConceptScore W1998293863C2776755682 @default.
- W1998293863 hasConceptScore W1998293863C2778695967 @default.
- W1998293863 hasConceptScore W1998293863C2780062018 @default.
- W1998293863 hasConceptScore W1998293863C41625074 @default.
- W1998293863 hasConceptScore W1998293863C513476851 @default.
- W1998293863 hasConceptScore W1998293863C55493867 @default.
- W1998293863 hasConceptScore W1998293863C86803240 @default.
- W1998293863 hasConceptScore W1998293863C99975950 @default.
- W1998293863 hasIssue "1" @default.
- W1998293863 hasLocation W19982938631 @default.
- W1998293863 hasLocation W19982938632 @default.
- W1998293863 hasOpenAccess W1998293863 @default.