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• W1998307533 abstract "Background An elevated thyroid stimulating hormone (TSH) level is a risk factor for differentiated thyroid cancer. The present study investigated whether TSH is a risk factor for thyroid microcarcinoma (TMC) in euthyroid subjects with a micronodule. Methods In this cross-sectional study, 483 euthyroid subjects (77 males patients, 406 females patients) with a thyroid micronodule were enrolled and underwent ultrasound guided fine-needle aspiration biopsy. Serum TSH level was measured in every subject. The final diagnostic outcome (malignant or benign) was defined in conjunction with cytology and histology. Results Compared with the patients below the population mean, patients above the population mean had a significantly higher malignancy rate (10.8% vs 4.8%, p = .025). Multiple logistic regression analysis revealed TSH as an independent risk factor for malignancy in euthyroid patients with a micronodule (odds ratio, 1.449; 95% confidence interval, 1.033–2.033; p = .031). Conclusions Measurement of TSH in subjects with a thyroid micronodule is helpful to estimate cancer risk. © 2011 Wiley Periodicals, Inc. Head Neck, 2012" @default.
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• W1998307533 date "2011-08-24" @default.
• W1998307533 modified "2023-09-25" @default.
• W1998307533 title "Serum thyrotropin as a risk factor for thyroid malignancy in euthyroid subjects with thyroid micronodule" @default.
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• W1998307533 doi "https://doi.org/10.1002/hed.21828" @default.
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