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- W1998326298 abstract "A 64-year-old man was admitted to our hosiptal because of possible liver cirrhosis. His serum cholinesterase was anomalously low with a ΔpH of 0.1 (normal range ; 0.8-1.1). His enzyme was more heat-labile than the normal controls. Km value of his enzyme for benzoylcholine was 1.1×10-5 mol/l, while that for normal controls was 2.3× 10-6 mol/l. In addition, isozymic alteration of his enzyme was observed. Sequencing of the white blood cell DNA of the patient showed a point mutation at nucleotide 1093 (GGA to CGA), which changes codon 365 from glycine to arginine.(Internal Medicine 31 : 357-362, 1992)" @default.
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- W1998326298 date "1992-01-01" @default.
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- W1998326298 title "A Variant Serum Cholinesterase and a Confirmed Point Mutation at Gly-365 to Arg Found in a Patient with Liver Cirrhosis." @default.
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- W1998326298 doi "https://doi.org/10.2169/internalmedicine.31.357" @default.
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