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• W1998332012 abstract "1 Pargyline treatment, 1 h before (+)-amphetamine (1 mg/kg), reduced amphetamine-stimulated motor activity. This inhibition was reversed in animals pretreated with p-chlorophenylalanine (PCPA).2 Following treatment with PCPA or 5,6-dihydroxytryptamine (5,6-DHT), amphetamine-induced locomotor activity was significantly potentiated. The increased response to amphetamine in PCPA-treated rats was reversed in animals pretreated with 5-hydroxytryptophan.3 The inhibition of amphetamine-stimulated locomotor activity by treatment with 6-hydroxydopamine was not reversed by PCPA treatment.4 Stereotypies produced by amphetamine were not found to be altered by depletion of 5-hydroxytryptamine.5 Induction of adrenal tyrosine hydroxylase activity produced by chronic amphetamine administration was significantly potentiated by PCPA, emphasizing the involvement of a 5-hydroxytryptamine inhibitory system in more than one action of amphetamine." @default.
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• W1998332012 date "1974-10-01" @default.
• W1998332012 modified "2023-09-24" @default.
• W1998332012 title "EVIDENCE FOR INVOLVEMENT OF 5-HYDROXYTRYPTAMINE IN THE ACTIONS OF AMPHETAMINE" @default.
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• W1998332012 doi "https://doi.org/10.1111/j.1476-5381.1974.tb09714.x" @default.
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