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• W1998367135 abstract "By a combination of different analytical methods, ecdysone and highly polar metabolites (HPP) were shown to be the predominant ecdysteroids in adult Tenebrio molitor. A distinct difference in the amount of ecdysteroid between males and females was observed. Tritium-labelled ecdysone was rapidly metabolized. Several compounds could be separated by HPTLC. Most of the [3H]material recovered from the insect was found in the HPP fraction. Since most of the injected [3H]material was excreted in the faeces as ecdysone (approx 65%), and HPP (approx 30%), a turnover of ecdysone into other ecdysteroids and vice versa seems possible. A new two-dimensional TLC method consisting of an initial run in a narrow strip of reversed phase media and another run in a conventional silica gel layer demonstrated that the main components of the tritiated materials were ecdysone and HPP, and that 20-hydroxyecdysone and 22,25-dideoxyecdysone were virtually absent. In males and females two HPP classes could be differentiated HPP I(′I) and HPP II(′II) and in females a third class was also present, HPP ′III. HPP I(′I) was the only class that was hydrolysable by several enzyme preparations (approx 30% of HPP), and was presumed to consist of glucuronides, β-glucosides and sulphate conjugates and was composed of ecdysone and two compounds with a higher polarity (CA and CB)." @default.
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• W1998367135 date "1983-01-01" @default.
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• W1998367135 title "Distribution and metabolism of ecdysteroids in the adult yellow mealworm beetle, Tenebrio molitor" @default.
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• W1998367135 doi "https://doi.org/10.1016/0020-1790(83)90010-0" @default.
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