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- W1998401227 abstract "Coeliac disease is an important cause of malabsorption, particularly of folic acid, in adults. We investigated the possibility that it might be a maternal risk factor for neural tube defect (NTD)-associated pregnancy by screening affected mothers using serum endomysial antibody (EmA) which has high sensitivity and specificity for coeliac disease. One (1.6%) of 60 patients was EmA positive and had a diagnosis of coeliac disease confirmed by the finding of villous atrophy on jejunal biopsy. In conclusion, the majority of NTD-associated pregnancies are not associated with maternal coeliac disease and our study is additional evidence that abnormalities of folic acid metabolism rather than absorption are the most important risk factors for NTD. Further studies are needed to determine whether the coeliac disease prevalence among women with NTD-affected pregnancy is higher than that of the general population." @default.
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- W1998401227 date "2008-04-23" @default.
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- W1998401227 title "Screening for coeliac disease as a possible maternal risk factor for neural tube defect" @default.
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- W1998401227 doi "https://doi.org/10.1111/j.1399-0004.1996.tb04339.x" @default.
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