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• W1998528712 abstract "Peptidylarginine deiminases (PADs) are a group of enzymes which convert protein arginine residues to citrulline residues. Using rat muscle PAD cDNA as a probe, we obtained two novel cDNAs, PAD‐R11 and PAD‐R4, from immortalized rat keratinocytes treated with all‐ trans retinoic acid. Comparison of the deduced amino acid sequences with those of muscle and hair follicle enzymes showed high conservation in the C‐terminal region. Recombinant proteins encoded by both PAD‐R11 and PAD‐R4 showed the enzyme activities. That of PAD‐R11 showed a characteristic feature of the enzyme found in the epidermis." @default.
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• W1998528712 date "1998-08-14" @default.
• W1998528712 modified "2023-10-15" @default.
• W1998528712 title "Molecular cloning of two novel types of peptidylarginine deiminase cDNAs from retinoic acid‐treated culture of a newborn rat keratinocyte cell line" @default.
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• W1998528712 doi "https://doi.org/10.1016/s0014-5793(98)00893-x" @default.
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