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• W1998536276 abstract "The headings describing the treatments in the last columns in Table 1, Table 2 of the above cited article are incorrect. The treatment is described in both cases as “Estriol gel 0.05%” where it should read “Estriol gel 0.005%”.Table 1Vaginal cytological transformation and uterine weight in rats after 14 days of treatment. Results are shown as the mean ± standard error of the mean of 10 animals per group (except absolute and sham control n = 5). Vaginal atrophy scores were compared with Kruskal–Wallis test with Dunn's correction for multiplicity. Uterine weights were compared by ANOVA with Bonferroni's correction for multiplicity.TreatmentAbsolute controlSham controlPlaceboOvestinon 0.1%Colpotrofin 1%Estriol gel 0.005%Vaginal atrophy score0.0 ± 0.0aNot significant against placebo.0.6 ± 0.2aNot significant against placebo.1.8 ± 0.23.0 ± 0.0bp<0.01 against placebo.3.0 ± 0.0bp<0.01 against placebo.2.9 ± 0.1cp<0.05 against placebo.Uterine weight0.116 ± 0.01aNot significant against placebo.0.109 ± 0.01aNot significant against placebo..0.110 ± 0.010.202 ± 0.02dp<0.001 against placebo.0.214 ± 0.02dp<0.001 against placebo.0.132 ± 0.01aNot significant against placebo.a Not significant against placebo.b p < 0.01 against placebo.c p < 0.05 against placebo.d p < 0.001 against placebo. Open table in a new tab Table 2Thickness of uteri myometrium, endometrium, total wall thickness and endometrial morphology score. Results are shown as the mean ± SEM. Histological characteristics affected in each case and their respective scoring are shown. Endometrial, myometrial and total wall thickness were compared by ANOVA with Bonferroni's correction for multiplicity global morphological scores were compared with Kruskal–Wallis test with Dunn's correction for multiplicity.TreatmentAbsolute controlSham controlPlaceboOvestinon 0.1%Colpotrofin 1%Estriol gel 0.005%Endometrial thickness (μm)266 ± 11aNot significant against placebo.262 ± 14aNot significant against placebo.270 ± 15454 ± 30dp<0.001 against placebo.622 ± 40dp<0.001 against placebo.321 ± 19aNot significant against placebo.Myometrial thickness (μm)180 ± 11)aNot significant against placebo.164 ± 16aNot significant against placebo.177 ± 11253 ± 23bp<0.05 against placebo.344 ± 27dp<0.001 against placebo.187 ± 13aNot significant against placebo.Total wall thickness (μm)444 ± 17aNot significant against placebo.424 ± 28aNot significant against placebo.447 ± 23707 ± 47dp<0.001 against placebo.964 ± 63dp<0.001 against placebo.508 ± 25aNot significant against placebo.Global morphological score0002.9 ± 0.38dp<0.001 against placebo.2.0 ± 0.30cp<0.01 against placebo.0.8 ± 0.33 Epithelial height0000.70.90 Nuclear position0000.60.40 Collagen0000.90.30.4 Endometrial eosinophilia0000.70.40.2a Not significant against placebo.b p < 0.05 against placebo.c p < 0.01 against placebo.d p < 0.001 against placebo. Open table in a new tab Comparative uterine effects on ovariectomized rats after repeated treatment with different vaginal estrogen formulationsMaturitasVol. 72Issue 4PreviewTopical estrogen therapy is recommended for the treatment of vaginal atrophy. This study was designed to compare the uterotrophic effects of a new estrogen vaginal formulation (0.005% estriol vaginal gel) and other existing topical treatments (Ovestinon® and Colpotrofin®). Full-Text PDF" @default.
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• W1998536276 date "2013-04-01" @default.
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• W1998536276 title "Corrigendum to “Comparative uterine effects on ovariectomized rats after repeated treatment with different vaginal estrogen formulations” [Maturitas 72 (2012) 353–358]" @default.
• W1998536276 doi "https://doi.org/10.1016/j.maturitas.2012.12.012" @default.
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