Matches in SemOpenAlex for { <https://semopenalex.org/work/W1998569388> ?p ?o ?g. }
- W1998569388 endingPage "328" @default.
- W1998569388 startingPage "323" @default.
- W1998569388 abstract "On the basis of morphologic and immunophenotypic studies, it is generally accepted that the lymphocyte population in thymomas is not neoplastic. We studied 10 thymomas with restriction endonuclease and Southern blot/DNA hybridization methods in an attempt to provide genotypic evidence in support of this hypothesis. The clinical, gross, and microscopic features of each case were reviewed and found to be entirely consistent with the diagnosis of thymoma. In addition to conventional histologic methods, we also studied each tumor by immunohistologic techniques. The lymphocytes generally had an immunotype characteristic of immature cortical thymocytes, and the epithelial cells were uniformly stained by antikeratin antibodies. DNA probes for the T-cell receptor β-chain gene and immunoglobulin genes (Ck, Cλ, and JH) were used in the genotypic studies. No gene rearrangements were detected in any of the thymomas. This study provides additional evidence that clonal proliferations of T or B lymphocytes are not present in thymomas; therefore, these cells are almost certainly not neoplastic. The results also provide a basis for the effective use of restriction endonuclease and Southern blot/DNA hybridization analysis in the differential diagnosis of non-Hodgkin's lymphoma and thymoma." @default.
- W1998569388 created "2016-06-24" @default.
- W1998569388 creator A5008134160 @default.
- W1998569388 creator A5059707915 @default.
- W1998569388 creator A5074992914 @default.
- W1998569388 creator A5089555088 @default.
- W1998569388 date "1988-03-01" @default.
- W1998569388 modified "2023-09-23" @default.
- W1998569388 title "Immunoglobulin and T-cell receptor genes inthymomas: Genotypic evidence supporting the nonneoplastic nature of the lymphocytic component" @default.
- W1998569388 cites W191476172 @default.
- W1998569388 cites W1974622261 @default.
- W1998569388 cites W1980927388 @default.
- W1998569388 cites W1989400464 @default.
- W1998569388 cites W1991052691 @default.
- W1998569388 cites W1996053148 @default.
- W1998569388 cites W1996905142 @default.
- W1998569388 cites W2002192875 @default.
- W1998569388 cites W2014669590 @default.
- W1998569388 cites W2014932087 @default.
- W1998569388 cites W2022186291 @default.
- W1998569388 cites W2022341531 @default.
- W1998569388 cites W2022654649 @default.
- W1998569388 cites W2025859483 @default.
- W1998569388 cites W2027067045 @default.
- W1998569388 cites W2030139848 @default.
- W1998569388 cites W2034220396 @default.
- W1998569388 cites W2045462207 @default.
- W1998569388 cites W2063450941 @default.
- W1998569388 cites W2064944485 @default.
- W1998569388 cites W2072083179 @default.
- W1998569388 cites W2074529126 @default.
- W1998569388 cites W2077682361 @default.
- W1998569388 cites W2079108495 @default.
- W1998569388 cites W2091566473 @default.
- W1998569388 cites W2106719152 @default.
- W1998569388 cites W2181087467 @default.
- W1998569388 cites W2316320702 @default.
- W1998569388 cites W2319793285 @default.
- W1998569388 cites W2335864563 @default.
- W1998569388 cites W2337101530 @default.
- W1998569388 cites W2337543356 @default.
- W1998569388 cites W2338997062 @default.
- W1998569388 cites W2340010154 @default.
- W1998569388 cites W2340094023 @default.
- W1998569388 cites W2460327172 @default.
- W1998569388 cites W52259325 @default.
- W1998569388 doi "https://doi.org/10.1016/s0046-8177(88)80526-4" @default.
- W1998569388 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2831135" @default.
- W1998569388 hasPublicationYear "1988" @default.
- W1998569388 type Work @default.
- W1998569388 sameAs 1998569388 @default.
- W1998569388 citedByCount "16" @default.
- W1998569388 crossrefType "journal-article" @default.
- W1998569388 hasAuthorship W1998569388A5008134160 @default.
- W1998569388 hasAuthorship W1998569388A5059707915 @default.
- W1998569388 hasAuthorship W1998569388A5074992914 @default.
- W1998569388 hasAuthorship W1998569388A5089555088 @default.
- W1998569388 hasConcept C104317684 @default.
- W1998569388 hasConcept C128319531 @default.
- W1998569388 hasConcept C133307689 @default.
- W1998569388 hasConcept C135763542 @default.
- W1998569388 hasConcept C142724271 @default.
- W1998569388 hasConcept C153911025 @default.
- W1998569388 hasConcept C159654299 @default.
- W1998569388 hasConcept C203014093 @default.
- W1998569388 hasConcept C2779159893 @default.
- W1998569388 hasConcept C2779338263 @default.
- W1998569388 hasConcept C54355233 @default.
- W1998569388 hasConcept C71924100 @default.
- W1998569388 hasConcept C86803240 @default.
- W1998569388 hasConceptScore W1998569388C104317684 @default.
- W1998569388 hasConceptScore W1998569388C128319531 @default.
- W1998569388 hasConceptScore W1998569388C133307689 @default.
- W1998569388 hasConceptScore W1998569388C135763542 @default.
- W1998569388 hasConceptScore W1998569388C142724271 @default.
- W1998569388 hasConceptScore W1998569388C153911025 @default.
- W1998569388 hasConceptScore W1998569388C159654299 @default.
- W1998569388 hasConceptScore W1998569388C203014093 @default.
- W1998569388 hasConceptScore W1998569388C2779159893 @default.
- W1998569388 hasConceptScore W1998569388C2779338263 @default.
- W1998569388 hasConceptScore W1998569388C54355233 @default.
- W1998569388 hasConceptScore W1998569388C71924100 @default.
- W1998569388 hasConceptScore W1998569388C86803240 @default.
- W1998569388 hasIssue "3" @default.
- W1998569388 hasLocation W19985693881 @default.
- W1998569388 hasLocation W19985693882 @default.
- W1998569388 hasOpenAccess W1998569388 @default.
- W1998569388 hasPrimaryLocation W19985693881 @default.
- W1998569388 hasRelatedWork W1508908385 @default.
- W1998569388 hasRelatedWork W1990502365 @default.
- W1998569388 hasRelatedWork W2009537141 @default.
- W1998569388 hasRelatedWork W2016821945 @default.
- W1998569388 hasRelatedWork W2028626100 @default.
- W1998569388 hasRelatedWork W2145368198 @default.
- W1998569388 hasRelatedWork W2158738420 @default.
- W1998569388 hasRelatedWork W2168934638 @default.
- W1998569388 hasRelatedWork W2321516259 @default.
- W1998569388 hasRelatedWork W2341696882 @default.