Matches in SemOpenAlex for { <https://semopenalex.org/work/W1998579972> ?p ?o ?g. }
- W1998579972 abstract "This study showed that clofazimine was not radiomimetic, it was not a mutagenic compound, it was not an inducer of prophage-lambda, and it did not eliminate plasmids from appropriate host bacteria. The drug caused an effective inhibition of the growth of Mycobacterium aurum, and also inhibited the growth cycle of the mycobacteriophage D29. Cross-resistance between clofazimine, streptomycin and rifampicin could not be demonstrated. Drug-resistance mutants towards clofazimine could not be isolated, and it was found that the existing clofazimine-resistant strains of Mycobacterium tuberculosis were rather susceptible organisms requiring clofazimine in their growth medium to maintain their drug-resistance. Ultrastructural studies showed that clofazimine did not act by cell wall lysis, nor did it act on bacterial ribosomes. Higher concentrations of the drug resulted in bacterial plasmolysis. These findings are discussed in the light of its known properties and proposed mode of action." @default.
- W1998579972 created "2016-06-24" @default.
- W1998579972 creator A5002453177 @default.
- W1998579972 creator A5046793258 @default.
- W1998579972 creator A5051476552 @default.
- W1998579972 creator A5079004330 @default.
- W1998579972 date "1987-08-01" @default.
- W1998579972 modified "2023-09-27" @default.
- W1998579972 title "Studies on clofazimine-resistance in mycobacteria: Is the inability to isolate drug-resistance mutants related to its mode of action?" @default.
- W1998579972 cites W1511401873 @default.
- W1998579972 cites W1516847164 @default.
- W1998579972 cites W1585208589 @default.
- W1998579972 cites W1810516835 @default.
- W1998579972 cites W1899702880 @default.
- W1998579972 cites W1973195696 @default.
- W1998579972 cites W1992782240 @default.
- W1998579972 cites W1998631074 @default.
- W1998579972 cites W2008244166 @default.
- W1998579972 cites W2008643214 @default.
- W1998579972 cites W2011996277 @default.
- W1998579972 cites W2017423124 @default.
- W1998579972 cites W2021836066 @default.
- W1998579972 cites W2023821800 @default.
- W1998579972 cites W2023990700 @default.
- W1998579972 cites W2032027769 @default.
- W1998579972 cites W2034033569 @default.
- W1998579972 cites W2044446186 @default.
- W1998579972 cites W2046945885 @default.
- W1998579972 cites W2057467251 @default.
- W1998579972 cites W2058607593 @default.
- W1998579972 cites W2064306389 @default.
- W1998579972 cites W2068270570 @default.
- W1998579972 cites W2085814996 @default.
- W1998579972 cites W2143692400 @default.
- W1998579972 cites W2144345256 @default.
- W1998579972 cites W2170343590 @default.
- W1998579972 cites W2334718098 @default.
- W1998579972 cites W2399319514 @default.
- W1998579972 cites W2405706384 @default.
- W1998579972 cites W2414594806 @default.
- W1998579972 doi "https://doi.org/10.1016/s0176-6724(87)80043-3" @default.
- W1998579972 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3122464" @default.
- W1998579972 hasPublicationYear "1987" @default.
- W1998579972 type Work @default.
- W1998579972 sameAs 1998579972 @default.
- W1998579972 citedByCount "2" @default.
- W1998579972 crossrefType "journal-article" @default.
- W1998579972 hasAuthorship W1998579972A5002453177 @default.
- W1998579972 hasAuthorship W1998579972A5046793258 @default.
- W1998579972 hasAuthorship W1998579972A5051476552 @default.
- W1998579972 hasAuthorship W1998579972A5079004330 @default.
- W1998579972 hasConcept C114851261 @default.
- W1998579972 hasConcept C142724271 @default.
- W1998579972 hasConcept C203014093 @default.
- W1998579972 hasConcept C2776297342 @default.
- W1998579972 hasConcept C2777975735 @default.
- W1998579972 hasConcept C2778607973 @default.
- W1998579972 hasConcept C2780374374 @default.
- W1998579972 hasConcept C2780695269 @default.
- W1998579972 hasConcept C2781069245 @default.
- W1998579972 hasConcept C3019249092 @default.
- W1998579972 hasConcept C501593827 @default.
- W1998579972 hasConcept C523546767 @default.
- W1998579972 hasConcept C54355233 @default.
- W1998579972 hasConcept C71924100 @default.
- W1998579972 hasConcept C86803240 @default.
- W1998579972 hasConcept C89423630 @default.
- W1998579972 hasConceptScore W1998579972C114851261 @default.
- W1998579972 hasConceptScore W1998579972C142724271 @default.
- W1998579972 hasConceptScore W1998579972C203014093 @default.
- W1998579972 hasConceptScore W1998579972C2776297342 @default.
- W1998579972 hasConceptScore W1998579972C2777975735 @default.
- W1998579972 hasConceptScore W1998579972C2778607973 @default.
- W1998579972 hasConceptScore W1998579972C2780374374 @default.
- W1998579972 hasConceptScore W1998579972C2780695269 @default.
- W1998579972 hasConceptScore W1998579972C2781069245 @default.
- W1998579972 hasConceptScore W1998579972C3019249092 @default.
- W1998579972 hasConceptScore W1998579972C501593827 @default.
- W1998579972 hasConceptScore W1998579972C523546767 @default.
- W1998579972 hasConceptScore W1998579972C54355233 @default.
- W1998579972 hasConceptScore W1998579972C71924100 @default.
- W1998579972 hasConceptScore W1998579972C86803240 @default.
- W1998579972 hasConceptScore W1998579972C89423630 @default.
- W1998579972 hasLocation W19985799721 @default.
- W1998579972 hasLocation W19985799722 @default.
- W1998579972 hasOpenAccess W1998579972 @default.
- W1998579972 hasPrimaryLocation W19985799721 @default.
- W1998579972 hasRelatedWork W1964584050 @default.
- W1998579972 hasRelatedWork W1989370000 @default.
- W1998579972 hasRelatedWork W1998579972 @default.
- W1998579972 hasRelatedWork W2102173040 @default.
- W1998579972 hasRelatedWork W2163030567 @default.
- W1998579972 hasRelatedWork W2346970938 @default.
- W1998579972 hasRelatedWork W2387697028 @default.
- W1998579972 hasRelatedWork W2389022559 @default.
- W1998579972 hasRelatedWork W2416380945 @default.
- W1998579972 hasRelatedWork W2432772203 @default.
- W1998579972 isParatext "false" @default.
- W1998579972 isRetracted "false" @default.
- W1998579972 magId "1998579972" @default.