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- W1998587092 abstract "The rates of biosynthesis of heme a and heme b in hearts of fed and fasted rats were measured using an isolated heart perfusion system. delta-Aminolevulinic acid synthetase activity was decreased in hearts of fasted rats to about 30% of values in hearts obtained from fed rats. [14C] Glycine incorporation into hemes a and b of cardiac tissue obtained from fasted rats was also decreased to about 30% of values obtained in hearts from fed rats. Cobalt addition to the perfusion fluid led to a decrease in cardiac delta-aminolevulinic acid synthetase activity just as cobalt administration to rats does in vivo. These studies strongly suggest that delta-aminolevulinic acid synthetase activity regulates the rate of synthesis of hemes a and b in the heart." @default.
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- W1998587092 date "1982-03-01" @default.
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- W1998587092 title "Heme biosynthesis in the heart" @default.
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- W1998587092 doi "https://doi.org/10.1016/0006-2952(82)90460-9" @default.
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