FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1998609784> ?p ?o ?g. }

• W1998609784 endingPage "NA" @default.
• W1998609784 startingPage "NA" @default.
• W1998609784 abstract "Minimally invasive subdermal injection of liquid silicone has been used clinically to augment the soft tissue of the foot to mitigate high pressures that cause diabetic foot ulcers. However, implant migration has been a clinical issue. The objective of this study was to assess the effects of three specific concentrations of silicone resin particles (12 mum average diameter) in conjunction with either platelet-derived growth factor (PDGF-BB) or basic fibroblast growth factor (bFGF) on fibroblast cell proliferation, collagen synthesis, cell morphology, and migration through in vitro assays and a monolayer scratch wound model. PDGF and bFGF enhanced the proliferation of fibroblasts 5.7-fold and fivefold, respectively, while the addition of silicone particles had no significant effect on proliferation. Collagen production was increased approximately twofold with the addition of bFGF and the medium concentration of particles over bFGF without particles and the PDGF groups. The addition of silicone particles had no significant effect on collagen production compared with control groups without particles. Fibroblast migration was enhanced by the addition of both PDGF and bFGF compared to controls, although slower scratch wound closure rates were observed in the presence of particles compared to controls without particles. Cell morphology suggested that particles induced cellular aggregation encircling silicone particles postwounding as well as migration into the wound area. These results suggest that silicone particles in combination with a growth factor might enhance fibroblast aggregation and implant stability, and could promote connective tissue ingrowth and implant encapsulation in the soft tissue of the diabetic foot." @default.
• W1998609784 created "2016-06-24" @default.
• W1998609784 creator A5003385153 @default.
• W1998609784 creator A5015650680 @default.
• W1998609784 creator A5034172336 @default.
• W1998609784 creator A5050990651 @default.
• W1998609784 creator A5066289226 @default.
• W1998609784 creator A5075735566 @default.
• W1998609784 date "2010-01-01" @default.
• W1998609784 modified "2023-09-26" @default.
• W1998609784 title "The characterization and optimization of injectable silicone resin particles in conjunction with dermal fibroblasts and growth factors: Anin vitrostudy" @default.
• W1998609784 cites W1592767674 @default.
• W1998609784 cites W1931315964 @default.
• W1998609784 cites W1969806743 @default.
• W1998609784 cites W1970024961 @default.
• W1998609784 cites W1976615140 @default.
• W1998609784 cites W1981097939 @default.
• W1998609784 cites W1983079870 @default.
• W1998609784 cites W1985527057 @default.
• W1998609784 cites W1988691104 @default.
• W1998609784 cites W1991613206 @default.
• W1998609784 cites W1998294992 @default.
• W1998609784 cites W2007692648 @default.
• W1998609784 cites W2008379117 @default.
• W1998609784 cites W2009449936 @default.
• W1998609784 cites W2015996457 @default.
• W1998609784 cites W2021489532 @default.
• W1998609784 cites W2022334495 @default.
• W1998609784 cites W2029874501 @default.
• W1998609784 cites W2030613512 @default.
• W1998609784 cites W2037629073 @default.
• W1998609784 cites W2050787387 @default.
• W1998609784 cites W2060338007 @default.
• W1998609784 cites W2062575512 @default.
• W1998609784 cites W2071438535 @default.
• W1998609784 cites W2071889889 @default.
• W1998609784 cites W2084334139 @default.
• W1998609784 cites W2087031595 @default.
• W1998609784 cites W2090642916 @default.
• W1998609784 cites W2100592123 @default.
• W1998609784 cites W2101004085 @default.
• W1998609784 cites W2110121929 @default.
• W1998609784 cites W2120500721 @default.
• W1998609784 cites W2127510940 @default.
• W1998609784 cites W2127621585 @default.
• W1998609784 cites W2138254084 @default.
• W1998609784 cites W2145689931 @default.
• W1998609784 cites W2165000537 @default.
• W1998609784 cites W2319534298 @default.
• W1998609784 cites W2418020630 @default.
• W1998609784 doi "https://doi.org/10.1002/jbm.b.31579" @default.
• W1998609784 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20091922" @default.
• W1998609784 hasPublicationYear "2010" @default.
• W1998609784 type Work @default.
• W1998609784 sameAs 1998609784 @default.
• W1998609784 citedByCount "1" @default.
• W1998609784 countsByYear W19986097842021 @default.
• W1998609784 crossrefType "journal-article" @default.
• W1998609784 hasAuthorship W1998609784A5003385153 @default.
• W1998609784 hasAuthorship W1998609784A5015650680 @default.
• W1998609784 hasAuthorship W1998609784A5034172336 @default.
• W1998609784 hasAuthorship W1998609784A5050990651 @default.
• W1998609784 hasAuthorship W1998609784A5066289226 @default.
• W1998609784 hasAuthorship W1998609784A5075735566 @default.
• W1998609784 hasConcept C12554922 @default.
• W1998609784 hasConcept C136229726 @default.
• W1998609784 hasConcept C141071460 @default.
• W1998609784 hasConcept C142724271 @default.
• W1998609784 hasConcept C159985019 @default.
• W1998609784 hasConcept C170493617 @default.
• W1998609784 hasConcept C180361614 @default.
• W1998609784 hasConcept C185592680 @default.
• W1998609784 hasConcept C192562407 @default.
• W1998609784 hasConcept C202751555 @default.
• W1998609784 hasConcept C203014093 @default.
• W1998609784 hasConcept C2775960820 @default.
• W1998609784 hasConcept C2777587049 @default.
• W1998609784 hasConcept C2779769944 @default.
• W1998609784 hasConcept C2780269544 @default.
• W1998609784 hasConcept C2780381497 @default.
• W1998609784 hasConcept C2781294074 @default.
• W1998609784 hasConcept C2781411149 @default.
• W1998609784 hasConcept C518705261 @default.
• W1998609784 hasConcept C55493867 @default.
• W1998609784 hasConcept C62112901 @default.
• W1998609784 hasConcept C71924100 @default.
• W1998609784 hasConcept C86803240 @default.
• W1998609784 hasConceptScore W1998609784C12554922 @default.
• W1998609784 hasConceptScore W1998609784C136229726 @default.
• W1998609784 hasConceptScore W1998609784C141071460 @default.
• W1998609784 hasConceptScore W1998609784C142724271 @default.
• W1998609784 hasConceptScore W1998609784C159985019 @default.
• W1998609784 hasConceptScore W1998609784C170493617 @default.
• W1998609784 hasConceptScore W1998609784C180361614 @default.
• W1998609784 hasConceptScore W1998609784C185592680 @default.
• W1998609784 hasConceptScore W1998609784C192562407 @default.
• W1998609784 hasConceptScore W1998609784C202751555 @default.
• W1998609784 hasConceptScore W1998609784C203014093 @default.

• next