Matches in SemOpenAlex for { <https://semopenalex.org/work/W1998618295> ?p ?o ?g. }
- W1998618295 endingPage "488" @default.
- W1998618295 startingPage "479" @default.
- W1998618295 abstract "Competing endogenous RNAs (ceRNAs) refer to RNA transcripts, such as mRNAs, non-coding RNAs, pseudogene transcripts, and circular RNAs, that can regulate each other by competing for the same pool of miRNAs. ceRNAs involve in the pathogenesis of several common cancers such as prostate cancer, liver cancer, breast cancer, lung cancer, gastric cancer, endometrial cancer, and so on. ceRNA activity is determined by factors such as miRNA/ceRNA abundance, ceRNAs binding affinity to miRNAs, RNA editing, and RNA-binding proteins. The alteration of any of these factors may lead to ceRNA network imbalance and thus contribute to cancer initiation and progression. There are generally three steps in ceRNA research conductions: ceRNA prediction, ceRNA validation, and ceRNA functional investigation. Deciphering ceRNA interplay in cancer provides new insight into cancer pathogenesis and opportunities for therapy exploration. In this review, we try to give readers a concise and reliable illustration on the mechanism, functions, research approaches, and perspective of ceRNA in cancer." @default.
- W1998618295 created "2016-06-24" @default.
- W1998618295 creator A5000870282 @default.
- W1998618295 creator A5012712390 @default.
- W1998618295 creator A5045405014 @default.
- W1998618295 creator A5057803786 @default.
- W1998618295 date "2015-01-22" @default.
- W1998618295 modified "2023-10-16" @default.
- W1998618295 title "Competing endogenous RNA interplay in cancer: mechanism, methodology, and perspectives" @default.
- W1998618295 cites W162041093 @default.
- W1998618295 cites W1965514608 @default.
- W1998618295 cites W1966498224 @default.
- W1998618295 cites W1971144342 @default.
- W1998618295 cites W1971623350 @default.
- W1998618295 cites W1973534708 @default.
- W1998618295 cites W1981613222 @default.
- W1998618295 cites W1986077139 @default.
- W1998618295 cites W1993799748 @default.
- W1998618295 cites W1996392642 @default.
- W1998618295 cites W2003723466 @default.
- W1998618295 cites W2004066250 @default.
- W1998618295 cites W2006556963 @default.
- W1998618295 cites W2007266898 @default.
- W1998618295 cites W2008976996 @default.
- W1998618295 cites W2012858030 @default.
- W1998618295 cites W2014311023 @default.
- W1998618295 cites W2017694461 @default.
- W1998618295 cites W2017768662 @default.
- W1998618295 cites W2028423947 @default.
- W1998618295 cites W2028755921 @default.
- W1998618295 cites W2034305079 @default.
- W1998618295 cites W2035528991 @default.
- W1998618295 cites W2046245088 @default.
- W1998618295 cites W2046387002 @default.
- W1998618295 cites W2046621435 @default.
- W1998618295 cites W2053003053 @default.
- W1998618295 cites W2054524196 @default.
- W1998618295 cites W2056846536 @default.
- W1998618295 cites W2058303505 @default.
- W1998618295 cites W2058835062 @default.
- W1998618295 cites W2059794606 @default.
- W1998618295 cites W2064165694 @default.
- W1998618295 cites W2069385510 @default.
- W1998618295 cites W2071714380 @default.
- W1998618295 cites W2072836911 @default.
- W1998618295 cites W2085401806 @default.
- W1998618295 cites W2087461579 @default.
- W1998618295 cites W2087718006 @default.
- W1998618295 cites W2088930981 @default.
- W1998618295 cites W2094892255 @default.
- W1998618295 cites W2095841868 @default.
- W1998618295 cites W2097627545 @default.
- W1998618295 cites W2099439961 @default.
- W1998618295 cites W2099915768 @default.
- W1998618295 cites W2102107106 @default.
- W1998618295 cites W2102482931 @default.
- W1998618295 cites W2103152808 @default.
- W1998618295 cites W2104806799 @default.
- W1998618295 cites W2106638896 @default.
- W1998618295 cites W2113582954 @default.
- W1998618295 cites W2117977572 @default.
- W1998618295 cites W2119802952 @default.
- W1998618295 cites W2122716364 @default.
- W1998618295 cites W2123285201 @default.
- W1998618295 cites W2135398049 @default.
- W1998618295 cites W2136222002 @default.
- W1998618295 cites W2141221830 @default.
- W1998618295 cites W2143145944 @default.
- W1998618295 cites W2146610020 @default.
- W1998618295 cites W2147806662 @default.
- W1998618295 cites W2148676014 @default.
- W1998618295 cites W2149748804 @default.
- W1998618295 cites W2150296976 @default.
- W1998618295 cites W2159793493 @default.
- W1998618295 cites W2162674813 @default.
- W1998618295 cites W2162681307 @default.
- W1998618295 cites W2163662536 @default.
- W1998618295 cites W2164780857 @default.
- W1998618295 cites W2259938310 @default.
- W1998618295 cites W3102334290 @default.
- W1998618295 cites W4238656497 @default.
- W1998618295 cites W4243176936 @default.
- W1998618295 cites W4255095925 @default.
- W1998618295 doi "https://doi.org/10.1007/s13277-015-3093-z" @default.
- W1998618295 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25604144" @default.
- W1998618295 hasPublicationYear "2015" @default.
- W1998618295 type Work @default.
- W1998618295 sameAs 1998618295 @default.
- W1998618295 citedByCount "110" @default.
- W1998618295 countsByYear W19986182952015 @default.
- W1998618295 countsByYear W19986182952016 @default.
- W1998618295 countsByYear W19986182952017 @default.
- W1998618295 countsByYear W19986182952018 @default.
- W1998618295 countsByYear W19986182952019 @default.
- W1998618295 countsByYear W19986182952020 @default.
- W1998618295 countsByYear W19986182952021 @default.
- W1998618295 countsByYear W19986182952022 @default.
- W1998618295 countsByYear W19986182952023 @default.