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• W1998695769 startingPage "1302" @default.
• W1998695769 abstract "In April 2007, there existed a repertory of 286 trials concerned with acute ischemic stroke on the Stroke Trials Registry (http://www.strokecenter.org/trials/), of which 209 trials were considered as complete (with no evidence of patient benefit unless one considers the much hard fought for and modest results of the tPA studies). Among other questions arising from such failures, one can wonder whether the plethora of pharmacological agents that exhibited neuroprotective properties in pre-clinical studies were selected for clinical trials entirely based upon their experimental efficacy. This mini-review will try to point out some of the weaknesses that could underline the failure of both researchers and clinicians involved in the field of stroke to obtain their ultimate goal--brain protection." @default.
• W1998695769 created "2016-06-24" @default.
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• W1998695769 date "2007-08-03" @default.
• W1998695769 modified "2023-10-16" @default.
• W1998695769 title "Neuroprotection and stroke: time for a compromise" @default.
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• W1998695769 doi "https://doi.org/10.1111/j.1471-4159.2007.04866.x" @default.
• W1998695769 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17727635" @default.
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