Matches in SemOpenAlex for { <https://semopenalex.org/work/W1998726657> ?p ?o ?g. }
- W1998726657 endingPage "447" @default.
- W1998726657 startingPage "443" @default.
- W1998726657 abstract "We examined the regulatory role of a reduction/oxidation (redox) control protein, thioredoxin (TRX), in tumor necrosis factor-α (TNF-α)-induced p38 MAP kinase activation and p38 MAP kinase-mediated cytokine expression utilizing TRX-transfected murine L929 cells (TRX14). The results showed that TNF-α-induced p38 MAP kinase activation and interleukin-6 (IL-6) production by TRX 14 were less than those by the parental L cells and the control transfected L cells (Neo-1). SB 203580 as the specific inhibitor for p38 MAP kinase activity inhibited TNF-α-induced IL-6 production by the parental L cells, indicating that TNF-α-activated p38 MAP kinase regulates IL-6 production by the cell lines used in this study. These results showed that overexpression of TRX negatively regulates p38 MAP kinase activation and p38 MAP kinase-mediated IL-6 production by TNF-α-stimulated cells, indicating that TRX is critical for p38 MAP kinase activation which regulates cytokine expression." @default.
- W1998726657 created "2016-06-24" @default.
- W1998726657 creator A5006350361 @default.
- W1998726657 creator A5012061869 @default.
- W1998726657 creator A5016294535 @default.
- W1998726657 creator A5041480913 @default.
- W1998726657 creator A5062685548 @default.
- W1998726657 creator A5074602663 @default.
- W1998726657 creator A5083020720 @default.
- W1998726657 creator A5083085591 @default.
- W1998726657 creator A5088723987 @default.
- W1998726657 date "1999-05-01" @default.
- W1998726657 modified "2023-10-18" @default.
- W1998726657 title "Thioredoxin Negatively Regulates p38 MAP Kinase Activation and IL-6 Production by Tumor Necrosis Factor-α" @default.
- W1998726657 cites W1554952666 @default.
- W1998726657 cites W1555938743 @default.
- W1998726657 cites W1587892340 @default.
- W1998726657 cites W1638074023 @default.
- W1998726657 cites W1842535138 @default.
- W1998726657 cites W1969268163 @default.
- W1998726657 cites W1969896862 @default.
- W1998726657 cites W1971076522 @default.
- W1998726657 cites W1978687973 @default.
- W1998726657 cites W1978690847 @default.
- W1998726657 cites W1989710374 @default.
- W1998726657 cites W2001399809 @default.
- W1998726657 cites W2007986629 @default.
- W1998726657 cites W2022914311 @default.
- W1998726657 cites W2023189063 @default.
- W1998726657 cites W2023312698 @default.
- W1998726657 cites W2025332686 @default.
- W1998726657 cites W2025548430 @default.
- W1998726657 cites W2032731042 @default.
- W1998726657 cites W2034580062 @default.
- W1998726657 cites W2037038152 @default.
- W1998726657 cites W2040071780 @default.
- W1998726657 cites W2045464500 @default.
- W1998726657 cites W2049370164 @default.
- W1998726657 cites W2065020384 @default.
- W1998726657 cites W2066560682 @default.
- W1998726657 cites W2102089891 @default.
- W1998726657 cites W2123791869 @default.
- W1998726657 cites W2130191484 @default.
- W1998726657 cites W2136953396 @default.
- W1998726657 cites W2137847377 @default.
- W1998726657 cites W2150627157 @default.
- W1998726657 cites W2162226205 @default.
- W1998726657 cites W4247896860 @default.
- W1998726657 doi "https://doi.org/10.1006/bbrc.1999.0658" @default.
- W1998726657 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10329406" @default.
- W1998726657 hasPublicationYear "1999" @default.
- W1998726657 type Work @default.
- W1998726657 sameAs 1998726657 @default.
- W1998726657 citedByCount "76" @default.
- W1998726657 countsByYear W19987266572012 @default.
- W1998726657 countsByYear W19987266572013 @default.
- W1998726657 countsByYear W19987266572014 @default.
- W1998726657 countsByYear W19987266572016 @default.
- W1998726657 countsByYear W19987266572017 @default.
- W1998726657 countsByYear W19987266572018 @default.
- W1998726657 countsByYear W19987266572021 @default.
- W1998726657 countsByYear W19987266572022 @default.
- W1998726657 crossrefType "journal-article" @default.
- W1998726657 hasAuthorship W1998726657A5006350361 @default.
- W1998726657 hasAuthorship W1998726657A5012061869 @default.
- W1998726657 hasAuthorship W1998726657A5016294535 @default.
- W1998726657 hasAuthorship W1998726657A5041480913 @default.
- W1998726657 hasAuthorship W1998726657A5062685548 @default.
- W1998726657 hasAuthorship W1998726657A5074602663 @default.
- W1998726657 hasAuthorship W1998726657A5083020720 @default.
- W1998726657 hasAuthorship W1998726657A5083085591 @default.
- W1998726657 hasAuthorship W1998726657A5088723987 @default.
- W1998726657 hasConcept C124160383 @default.
- W1998726657 hasConcept C132149769 @default.
- W1998726657 hasConcept C137361374 @default.
- W1998726657 hasConcept C138227536 @default.
- W1998726657 hasConcept C153911025 @default.
- W1998726657 hasConcept C159479382 @default.
- W1998726657 hasConcept C163035849 @default.
- W1998726657 hasConcept C17991360 @default.
- W1998726657 hasConcept C181199279 @default.
- W1998726657 hasConcept C184235292 @default.
- W1998726657 hasConcept C203014093 @default.
- W1998726657 hasConcept C2778690821 @default.
- W1998726657 hasConcept C3623737 @default.
- W1998726657 hasConcept C502942594 @default.
- W1998726657 hasConcept C51551487 @default.
- W1998726657 hasConcept C55493867 @default.
- W1998726657 hasConcept C59143045 @default.
- W1998726657 hasConcept C82495950 @default.
- W1998726657 hasConcept C86803240 @default.
- W1998726657 hasConcept C90934575 @default.
- W1998726657 hasConcept C95444343 @default.
- W1998726657 hasConcept C97029542 @default.
- W1998726657 hasConceptScore W1998726657C124160383 @default.
- W1998726657 hasConceptScore W1998726657C132149769 @default.
- W1998726657 hasConceptScore W1998726657C137361374 @default.
- W1998726657 hasConceptScore W1998726657C138227536 @default.