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- W1998735833 abstract "The gross and histological features of congenital lipoprotein lipase deficiency are described in eight cats. The main histological features could be directly related to the presence of the chylomicronaemia. They consisted of lipid accumulation within clear vacuoles or ceroid accumulation within residual bodies in parenchymatous organs such as the liver, spleen, lymph nodes, kidney and adrenal gland. Xanthomata were seen in various sites, probably arising either from frank haemorrhage or the leakage of lipid-rich plasma perivascularly. As in human lipoprotein lipase deficiency there was no evidence of the formation of atherosclerotic plaques. Focal degenerative changes were, however, present within arteries and this may indicate blood vessel weakness and explain the tendency to haemorrhage and xanthomata/granulomata formation. The degeneration and fibrous replacement of glomeruli and nephrons possibly arises ti'om pressure necrosis of adjacent xanthomata and alterations in renal blood flow." @default.
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- W1998735833 date "1990-02-01" @default.
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- W1998735833 title "The pathology of an inherited hyperlipoproteinaemia of cats" @default.
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- W1998735833 doi "https://doi.org/10.1016/s0021-9975(08)80118-1" @default.
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