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- W1998769985 abstract "The effects of high molecular weight dextran sulphate (DXS) on the migration of 125I-labelled deoxyuridine-labelled peripheral lymphoblasts (stimulated by oxazolone) were studied in vivo by injecting the drug (50 mg/kg) subcutaneously in recipients, and by following the fate of oxazolone-stimulated peripheral lymphocytes treated in vitro with DXS in non-treated syngeneic recipients. Both types of experiments demonstrate that DXS considerably reduces lymphoblast extravasation in skin sites inflamed either by non-immune causes or by DTH. Our results also demonstrate that oxazolone-stimulated peripheral lymphocytes, after in vitro treatment with DXS, are unable to transfer antigen-specific contact hypersensitivity to unsensitized recipients. The results obtained suggest that the drug acts on both T effector cells and lymphoblasts." @default.
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- W1998769985 date "1987-06-01" @default.
- W1998769985 modified "2023-09-27" @default.
- W1998769985 title "Effects of dextran sulphate on lymphoblast extravasation into inflammatory skin sites" @default.
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- W1998769985 doi "https://doi.org/10.1016/0162-3109(87)90055-5" @default.
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