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- W1998771657 abstract "The synthesis of 5-N-Methylaminosulfonylmethyl-3-(N-methylpyrrolidin-2-ylmethyl)indole (1), a conformationally restricted analog of the anti-migraine drug, sumatriptan, is described. To incorporate our novel stereogenic replacement for the aminoethyl sidechain in sumatriptan, a convergent synthesis of the 3,5-disubstituted indole (1) was employed which utilized an intramolecular Heck reaction as the cornerstone reaction." @default.
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- W1998771657 date "1992-12-01" @default.
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- W1998771657 title "The synthesis of a conformationally restricted analog of the anti-migraine drug sumatriptan" @default.
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- W1998771657 doi "https://doi.org/10.1016/s0040-4039(00)74703-4" @default.
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