Matches in SemOpenAlex for { <https://semopenalex.org/work/W1998774893> ?p ?o ?g. }
Showing items 1 to 56 of
56
with 100 items per page.
- W1998774893 abstract "Proteomics is a relatively new fixture in the toolbox used to study the kidney. It is a scant 13 years since the term proteomics first was applied to the study of proteins on a global scale. 1 The term proteomics entered the renal lexicon in a prescient article authored by Mark Knepper in which he noted the potential of the approach to help understand the kidney. 2 Since that time the use of proteomic techniques in kidney research has increased dramatically. Initial studies leaned heavily on 2-dimensional gel electrophoresis methods for protein separation and quantitation, whereas protein identification was performed primarily with peptide mass fingerprinting techniques. 3 These approaches were useful, but had limited sensitivity and allowed characterization of only several hundred protein forms in a single experiment. Recent advances in protein separation and mass spectrometry have resulted in the implementation of so-called shotgun proteomic techniques capable of characterizing several thousand proteins in a single analysis. 4 As new and more powerful methods have become available, we have seen a shift to the study of human specimens and the beginnings of clinical proteomics in nephrology. 5,6 This issue of Seminars in Nephrology reflects that evolution. The first series of articles summarizes new approaches to proteomic methodology in the kidney and urine. Included in this section are 3 emerging techniques: metabolomics, imaging mass spectrometry, and differential calorimetry, which are powerful complements to standard proteomic methods. In the second section, we summarize developments in the specific areas of pediatric disease, diabetic nephropathy, and acute kidney injury. Ultimately, we hope these articles provide valuable information about current and developing proteomic tools and how they provide new insights into renal disease." @default.
- W1998774893 created "2016-06-24" @default.
- W1998774893 creator A5005864499 @default.
- W1998774893 date "2007-11-01" @default.
- W1998774893 modified "2023-09-27" @default.
- W1998774893 title "Proteomics and the Kidney: An Evolution" @default.
- W1998774893 cites W1987083564 @default.
- W1998774893 cites W1994802428 @default.
- W1998774893 cites W2024141877 @default.
- W1998774893 cites W2037791286 @default.
- W1998774893 cites W2127151284 @default.
- W1998774893 cites W2171215275 @default.
- W1998774893 doi "https://doi.org/10.1016/j.semnephrol.2007.09.007" @default.
- W1998774893 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18061839" @default.
- W1998774893 hasPublicationYear "2007" @default.
- W1998774893 type Work @default.
- W1998774893 sameAs 1998774893 @default.
- W1998774893 citedByCount "0" @default.
- W1998774893 crossrefType "journal-article" @default.
- W1998774893 hasAuthorship W1998774893A5005864499 @default.
- W1998774893 hasConcept C104317684 @default.
- W1998774893 hasConcept C126322002 @default.
- W1998774893 hasConcept C2780091579 @default.
- W1998774893 hasConcept C46111723 @default.
- W1998774893 hasConcept C55493867 @default.
- W1998774893 hasConcept C60644358 @default.
- W1998774893 hasConcept C70721500 @default.
- W1998774893 hasConcept C71924100 @default.
- W1998774893 hasConcept C86803240 @default.
- W1998774893 hasConceptScore W1998774893C104317684 @default.
- W1998774893 hasConceptScore W1998774893C126322002 @default.
- W1998774893 hasConceptScore W1998774893C2780091579 @default.
- W1998774893 hasConceptScore W1998774893C46111723 @default.
- W1998774893 hasConceptScore W1998774893C55493867 @default.
- W1998774893 hasConceptScore W1998774893C60644358 @default.
- W1998774893 hasConceptScore W1998774893C70721500 @default.
- W1998774893 hasConceptScore W1998774893C71924100 @default.
- W1998774893 hasConceptScore W1998774893C86803240 @default.
- W1998774893 hasLocation W19987748931 @default.
- W1998774893 hasLocation W19987748932 @default.
- W1998774893 hasOpenAccess W1998774893 @default.
- W1998774893 hasPrimaryLocation W19987748931 @default.
- W1998774893 hasRelatedWork W1614434693 @default.
- W1998774893 hasRelatedWork W2080856312 @default.
- W1998774893 hasRelatedWork W2088324202 @default.
- W1998774893 hasRelatedWork W2153167812 @default.
- W1998774893 hasRelatedWork W2161712355 @default.
- W1998774893 hasRelatedWork W2184494729 @default.
- W1998774893 hasRelatedWork W2341060983 @default.
- W1998774893 hasRelatedWork W2379886502 @default.
- W1998774893 hasRelatedWork W3187594710 @default.
- W1998774893 hasRelatedWork W4248659496 @default.
- W1998774893 isParatext "false" @default.
- W1998774893 isRetracted "false" @default.
- W1998774893 magId "1998774893" @default.
- W1998774893 workType "article" @default.