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- W1998779563 abstract "Abstract Ultrasound has been used to selectively lesion the corpus callosum in 18 rats. A focused beam, at 3.3 MHz of 3.5 W total acoustic output with 2 sec continuous wave exposure, was used to create approximately spherical lesions of 1 mm diameter. A series of overlapping lesions enabled severance of the entire corpus callosum at the midline. To make the technique more reliable an ultrasonic method was developed to accurately locate the corpus callosum. Verification of the lesions was made histologically and also electrophysiologically by observing the disappearance of trans-callosal evoked potentials. Damage to fibres other than the corpus callosum was minimal. Possible applications of this lesioning technique are mentioned." @default.
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- W1998779563 date "1980-01-01" @default.
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- W1998779563 title "Split-brain preparation by ultrasonic lesions in the rat" @default.
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- W1998779563 doi "https://doi.org/10.1016/0031-9384(80)90023-2" @default.
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