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• W1998781337 abstract "The loading and containment of cargo within nanoparticles and their efficient delivery to cells represent a primary challenge in nanomedicine. We report lipid exchange between free and mesoporous silica nanoparticle-supported lipid bilayers as an effective means of containing cargo, controlling charge, and directing delivery to mammalian cells. The delivery of a membrane-impermeable dye (calcein) and a chemotherapeutic drug (doxorubicin) are demonstrated. Exchanged lipid bilayers minimized premature drug release, and an overall positive charge on the supported lipid bilayer effected enhanced delivery." @default.
• W1998781337 created "2016-06-24" @default.
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• W1998781337 date "2009-05-15" @default.
• W1998781337 modified "2023-10-07" @default.
• W1998781337 title "Electrostatically Mediated Liposome Fusion and Lipid Exchange with a Nanoparticle-Supported Bilayer for Control of Surface Charge, Drug Containment, and Delivery" @default.
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• W1998781337 doi "https://doi.org/10.1021/ja902039y" @default.
• W1998781337 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2724844" @default.
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