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- W1998806601 abstract "H E R e E S S ~ M r, L E X virus infect ions general ly involve skin and mucous m e m b r a n e s and usually produce a selfl imiting disease. 1 Extensive local infect ion or dissemina ted visceral disease occurs more f requent ly in n e w b o r n infants,'-' severely malnour i shed children, 3 persons undergoing immunosuppress ive therapy, 4 and pa t ien ts with various cellular i m m u n e defec t s ) In chi ldren with leukemia, extensive local skin manifes ta t ions of HSV infection occur, but the occurrence of f u lminan t hepatoadrenal necrosis and DIC is rare. We report d isseminated HSV type 1 infect ion that involved liver, adrena l glands, and skin in associat ion with acute lymphocyt ic leukemia. Early recogni t ion o f the disease using electron microscopy and p r o m p t inst i tut ion of therapy with adenosine arabinos ide failed to p roduce a favorable response." @default.
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- W1998806601 date "1977-11-01" @default.
- W1998806601 modified "2023-09-27" @default.
- W1998806601 title "Disseminated herpes simplex with hepatoadrenal necrosis in a child with acute leukemia" @default.
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- W1998806601 doi "https://doi.org/10.1016/s0022-3476(77)81032-9" @default.
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