FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1998808512> ?p ?o ?g. }

• W1998808512 endingPage "586" @default.
• W1998808512 startingPage "578" @default.
• W1998808512 abstract "Rationale: The effects of high positive end-expiratory pressure (PEEP) strictly depend on lung recruitability, which varies widely during acute respiratory distress syndrome (ARDS). Unfortunately, increasing PEEP may lead to opposing effects on two main factors potentially worsening the lung injury, that is, alveolar strain and intratidal opening and closing, being detrimental (increasing the former) or beneficial (decreasing the latter).Objectives: To investigate how lung recruitability influences alveolar strain and intratidal opening and closing after the application of high PEEP.Methods: We analyzed data from a database of 68 patients with acute lung injury or ARDS who underwent whole-lung computed tomography at 5, 15, and 45 cm H2O airway pressure.Measurements and Main Results: End-inspiratory nonaerated lung tissue was estimated from computed tomography pressure–volume curves. Alveolar strain and opening and closing lung tissue were computed at 5 and 15 cm H2O PEEP. In patients with a higher percentage of potentially recruitable lung, the increase in PEEP markedly reduced opening and closing lung tissue (P < 0.001), whereas no differences were observed in patients with a lower percentage of potentially recruitable lung. In contrast, alveolar strain similarly increased in the two groups (P = 0.89). Opening and closing lung tissue was distributed mainly in the dependent and hilar lung regions, and it appeared to be an independent risk factor for death (odds ratio, 1.10 for each 10-g increase).Conclusions: In ARDS, especially in patients with higher lung recruitability, the beneficial impact of reducing intratidal alveolar opening and closing by increasing PEEP prevails over the effects of increasing alveolar strain." @default.
• W1998808512 created "2016-06-24" @default.
• W1998808512 creator A5011914806 @default.
• W1998808512 creator A5028133692 @default.
• W1998808512 creator A5037669071 @default.
• W1998808512 creator A5040529274 @default.
• W1998808512 creator A5042853510 @default.
• W1998808512 creator A5050616784 @default.
• W1998808512 creator A5053616349 @default.
• W1998808512 creator A5060255856 @default.
• W1998808512 creator A5064447249 @default.
• W1998808512 creator A5074000031 @default.
• W1998808512 creator A5084652949 @default.
• W1998808512 creator A5086335943 @default.
• W1998808512 date "2010-03-15" @default.
• W1998808512 modified "2023-10-15" @default.
• W1998808512 title "Lung Opening and Closing during Ventilation of Acute Respiratory Distress Syndrome" @default.
• W1998808512 cites W1788732318 @default.
• W1998808512 cites W1823772832 @default.
• W1998808512 cites W1940579175 @default.
• W1998808512 cites W1977037251 @default.
• W1998808512 cites W1990202497 @default.
• W1998808512 cites W1993173897 @default.
• W1998808512 cites W2006109339 @default.
• W1998808512 cites W2009478257 @default.
• W1998808512 cites W2026595700 @default.
• W1998808512 cites W2029613254 @default.
• W1998808512 cites W2037459166 @default.
• W1998808512 cites W2045749178 @default.
• W1998808512 cites W2053066034 @default.
• W1998808512 cites W2062141566 @default.
• W1998808512 cites W2068086021 @default.
• W1998808512 cites W2093480593 @default.
• W1998808512 cites W2100688873 @default.
• W1998808512 cites W2109704422 @default.
• W1998808512 cites W2113752525 @default.
• W1998808512 cites W2115303739 @default.
• W1998808512 cites W2116685432 @default.
• W1998808512 cites W2118357854 @default.
• W1998808512 cites W2120076396 @default.
• W1998808512 cites W2120751481 @default.
• W1998808512 cites W2124098901 @default.
• W1998808512 cites W2125351007 @default.
• W1998808512 cites W2127471338 @default.
• W1998808512 cites W2139350281 @default.
• W1998808512 cites W2148493977 @default.
• W1998808512 cites W2154581887 @default.
• W1998808512 cites W2157545462 @default.
• W1998808512 cites W2161328469 @default.
• W1998808512 cites W2167718580 @default.
• W1998808512 cites W2167743972 @default.
• W1998808512 cites W2168829312 @default.
• W1998808512 cites W2170425345 @default.
• W1998808512 cites W2333411966 @default.
• W1998808512 cites W4237055469 @default.
• W1998808512 cites W4247943214 @default.
• W1998808512 cites W4251110202 @default.
• W1998808512 doi "https://doi.org/10.1164/rccm.200905-0787oc" @default.
• W1998808512 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19910610" @default.
• W1998808512 hasPublicationYear "2010" @default.
• W1998808512 type Work @default.
• W1998808512 sameAs 1998808512 @default.
• W1998808512 citedByCount "282" @default.
• W1998808512 countsByYear W19988085122012 @default.
• W1998808512 countsByYear W19988085122013 @default.
• W1998808512 countsByYear W19988085122014 @default.
• W1998808512 countsByYear W19988085122015 @default.
• W1998808512 countsByYear W19988085122016 @default.
• W1998808512 countsByYear W19988085122017 @default.
• W1998808512 countsByYear W19988085122018 @default.
• W1998808512 countsByYear W19988085122019 @default.
• W1998808512 countsByYear W19988085122020 @default.
• W1998808512 countsByYear W19988085122021 @default.
• W1998808512 countsByYear W19988085122022 @default.
• W1998808512 countsByYear W19988085122023 @default.
• W1998808512 crossrefType "journal-article" @default.
• W1998808512 hasAuthorship W1998808512A5011914806 @default.
• W1998808512 hasAuthorship W1998808512A5028133692 @default.
• W1998808512 hasAuthorship W1998808512A5037669071 @default.
• W1998808512 hasAuthorship W1998808512A5040529274 @default.
• W1998808512 hasAuthorship W1998808512A5042853510 @default.
• W1998808512 hasAuthorship W1998808512A5050616784 @default.
• W1998808512 hasAuthorship W1998808512A5053616349 @default.
• W1998808512 hasAuthorship W1998808512A5060255856 @default.
• W1998808512 hasAuthorship W1998808512A5064447249 @default.
• W1998808512 hasAuthorship W1998808512A5074000031 @default.
• W1998808512 hasAuthorship W1998808512A5084652949 @default.
• W1998808512 hasAuthorship W1998808512A5086335943 @default.
• W1998808512 hasConcept C126322002 @default.
• W1998808512 hasConcept C127413603 @default.
• W1998808512 hasConcept C141983124 @default.
• W1998808512 hasConcept C200457457 @default.
• W1998808512 hasConcept C27101514 @default.
• W1998808512 hasConcept C2776348555 @default.
• W1998808512 hasConcept C2777080012 @default.
• W1998808512 hasConcept C2777714996 @default.
• W1998808512 hasConcept C2778917391 @default.
• W1998808512 hasConcept C2909621147 @default.

• next