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- W1998828538 endingPage "45" @default.
- W1998828538 startingPage "38" @default.
- W1998828538 abstract "Fluid homeostasis in vertebrates critically relies on the lymphatic system forming a hierarchical network of lymphatic capillaries and collecting lymphatics, for the efficient drainage and transport of extravasated fluid back to the cardiovascular system. Blind-ended lymphatic capillaries employ specialized junctions and anchoring filaments to encourage a unidirectional flow of the interstitial fluid into the initial lymphatic vessels, whereas collecting lymphatics are responsible for the active propulsion of the lymph to the venous circulation via the combined action of lymphatic muscle cells and intraluminal valves. Here we describe recent findings on molecular and physical factors regulating the development and maturation of these two types of valves and examine their role in tissue-fluid homeostasis." @default.
- W1998828538 created "2016-06-24" @default.
- W1998828538 creator A5051061121 @default.
- W1998828538 creator A5080273121 @default.
- W1998828538 creator A5088766618 @default.
- W1998828538 date "2014-11-01" @default.
- W1998828538 modified "2023-10-16" @default.
- W1998828538 title "Primary and secondary lymphatic valve development: Molecular, functional and mechanical insights" @default.
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- W1998828538 doi "https://doi.org/10.1016/j.mvr.2014.07.008" @default.
- W1998828538 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4490164" @default.
- W1998828538 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25086182" @default.