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• W1998834963 abstract "During meiotic nuclear envelope breakdown (NEBD) in maturing oocytes of the surf clam, Spisula solidissima, the 67-kDa lamin is extensively phosphorylated, concurrently with its solubilization. This is accompanied by a reduction of the nuclear diameter. Quercetin, a protein kinase inhibitor, does not affect lamin phosphorylation and release, nor NEBD per se, but specifically inhibits the early phosphorylation of a set of proteins, on which NEBD seems to depend. Our results suggest that meiotic NEBD in Spisula oocytes may be controlled by a mechanism which involves lamin phosphorylation, similar to that which is thought to operate in mitosis." @default.
• W1998834963 created "2016-06-24" @default.
• W1998834963 creator A5004905921 @default.
• W1998834963 creator A5048193848 @default.
• W1998834963 date "1988-12-01" @default.
• W1998834963 modified "2023-10-10" @default.
• W1998834963 title "Meiotic breakdown of nuclear envelope in oocytes of Spisula solidissima involves phosphorylation and release of nuclear lamin" @default.
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• W1998834963 doi "https://doi.org/10.1016/0012-1606(88)90349-1" @default.
• W1998834963 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3058543" @default.
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