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- W1998870115 abstract "Pyrroloindoles are a key structural motif found in a wide number of biologically active alkaloids. Intramolecular copper-catalyzed coupling of readily accessible 2-iodo-tryptophan derivatives occurs in excellent yield, affording a wide range of polysubstituted, enantioenriched tetrahydropyrrolo[2,3-b]indoles. Diketopiperazines are also suitable substrates for this cyclization reaction, which affords a straightforward entry to tetra- to hepta-polycyclic systems." @default.
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- W1998870115 date "2008-08-06" @default.
- W1998870115 modified "2023-10-07" @default.
- W1998870115 title "Copper-Catalyzed Cyclization of Iodo-tryptophans: A Straightforward Synthesis of Pyrroloindoles" @default.
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- W1998870115 doi "https://doi.org/10.1021/ol8015513" @default.
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