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- W1998879489 abstract "RATIONALE: Autoimmune thyroid disease with elevated anti-thyroid antibodies has been implicated as a cause of chronic urticaria (CU). We examined the incidence of thyroid autoimmunity in patients with CU in the Lebanese population. METHODS: A retrospective chart review was conducted on 90 patients with CU at the allergy clinic of our hospital. Anti-peroxidase antibodies, TSH and freeT4 were measured. The diagnosis of thyroid autoimmunity was made by a level of anti-peroxidase antibodies above 100 IU/ml. RESULTS: Sixteen patients (17.7%) had high levels of anti-peroxidase antibodies.This is significantly higher than the normal population (p <0.01by χ2 test) if we compare our results to a study done by Halaby et al (submitted) where 60 (8.77%) out of 684 healthy subjects had positive anti-peroxidase antibodies. A comparison made with NHANES III, shows similar results (p < 0.04). CONCLUSIONS: To our knowledge this is the first study done in Lebanon showing the higher incidence of auto-immune thyroid disease in patients with CU compared to the normal population. It justifies the measurement of anti-thyroid antibodies when evaluating a patient with CU, an approach not practiced routinely in Lebanon, although recommended before by Sussman and Leznoff. This study might have a major impact on diagnosis and treatment of CU in Lebanon." @default.
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- W1998879489 date "2009-02-01" @default.
- W1998879489 modified "2023-09-27" @default.
- W1998879489 title "Chronic Urticaria and Autoimmune Thyroid Disease in Lebanon" @default.
- W1998879489 doi "https://doi.org/10.1016/j.jaci.2008.12.380" @default.
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