Matches in SemOpenAlex for { <https://semopenalex.org/work/W1998889274> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W1998889274 abstract "Three gadolinium-labeled compounds, potential nuclear magnetic resonance (NMR) imaging contrast agents for liver and biliary tract, were studied: 1 Gd-DISIDA, 2( Gd-DTPA-Liposomes, and 3) Gd-DTPA dihexadecylamide (Gd-diamide). In each case, “Carrier Added” Gd-153 with specific activity of about 5uCi/mg was used. Each labeled compound was evaluated in experimental animals. Gd-DISIDA proved unsatisfactory because of in vivo instability. Gd-DTPA-Liposomes demonstrated strong toxic effects probably due to pulmonary embolism when large amounts of this compound was administered intravenously. Gd-diamide showed good uptake in the hepatocytes with subsequent excretion into the biliary tract. Several rabbits were imaged in a 0.6T NMR imaging system before and after injection of Gd-diamide. Pulse sequences were chosen that would yield T1-weighted images and permit calculation of T1 relaxation times. This compound produced significant shortening of the T1 relaxation times of the liver and observable increase in intensity on the T1-weighted images. Gd-diamide shows promise as potential NMR contrast agent for liver and biliary tract imaging." @default.
- W1998889274 created "2016-06-24" @default.
- W1998889274 creator A5026815081 @default.
- W1998889274 creator A5042023490 @default.
- W1998889274 creator A5072721916 @default.
- W1998889274 date "1987-09-01" @default.
- W1998889274 modified "2023-10-06" @default.
- W1998889274 title "Gadolinium labeled pharmaceuticals as potential mri contrast agents for liver and biliary tract" @default.
- W1998889274 cites W1990050955 @default.
- W1998889274 cites W2011832860 @default.
- W1998889274 cites W2042653120 @default.
- W1998889274 cites W2088307137 @default.
- W1998889274 cites W2479592380 @default.
- W1998889274 doi "https://doi.org/10.1002/jlcr.2580240915" @default.
- W1998889274 hasPublicationYear "1987" @default.
- W1998889274 type Work @default.
- W1998889274 sameAs 1998889274 @default.
- W1998889274 citedByCount "3" @default.
- W1998889274 countsByYear W19988892742019 @default.
- W1998889274 crossrefType "journal-article" @default.
- W1998889274 hasAuthorship W1998889274A5026815081 @default.
- W1998889274 hasAuthorship W1998889274A5042023490 @default.
- W1998889274 hasAuthorship W1998889274A5072721916 @default.
- W1998889274 hasConcept C121332964 @default.
- W1998889274 hasConcept C126322002 @default.
- W1998889274 hasConcept C126838900 @default.
- W1998889274 hasConcept C143409427 @default.
- W1998889274 hasConcept C150903083 @default.
- W1998889274 hasConcept C178790620 @default.
- W1998889274 hasConcept C185154212 @default.
- W1998889274 hasConcept C185592680 @default.
- W1998889274 hasConcept C197404232 @default.
- W1998889274 hasConcept C207001950 @default.
- W1998889274 hasConcept C2775982439 @default.
- W1998889274 hasConcept C2778931785 @default.
- W1998889274 hasConcept C2989005 @default.
- W1998889274 hasConcept C46141821 @default.
- W1998889274 hasConcept C55493867 @default.
- W1998889274 hasConcept C557651011 @default.
- W1998889274 hasConcept C71924100 @default.
- W1998889274 hasConcept C86803240 @default.
- W1998889274 hasConceptScore W1998889274C121332964 @default.
- W1998889274 hasConceptScore W1998889274C126322002 @default.
- W1998889274 hasConceptScore W1998889274C126838900 @default.
- W1998889274 hasConceptScore W1998889274C143409427 @default.
- W1998889274 hasConceptScore W1998889274C150903083 @default.
- W1998889274 hasConceptScore W1998889274C178790620 @default.
- W1998889274 hasConceptScore W1998889274C185154212 @default.
- W1998889274 hasConceptScore W1998889274C185592680 @default.
- W1998889274 hasConceptScore W1998889274C197404232 @default.
- W1998889274 hasConceptScore W1998889274C207001950 @default.
- W1998889274 hasConceptScore W1998889274C2775982439 @default.
- W1998889274 hasConceptScore W1998889274C2778931785 @default.
- W1998889274 hasConceptScore W1998889274C2989005 @default.
- W1998889274 hasConceptScore W1998889274C46141821 @default.
- W1998889274 hasConceptScore W1998889274C55493867 @default.
- W1998889274 hasConceptScore W1998889274C557651011 @default.
- W1998889274 hasConceptScore W1998889274C71924100 @default.
- W1998889274 hasConceptScore W1998889274C86803240 @default.
- W1998889274 hasLocation W19988892741 @default.
- W1998889274 hasOpenAccess W1998889274 @default.
- W1998889274 hasPrimaryLocation W19988892741 @default.
- W1998889274 hasRelatedWork W101542673 @default.
- W1998889274 hasRelatedWork W1969251429 @default.
- W1998889274 hasRelatedWork W1977824093 @default.
- W1998889274 hasRelatedWork W1987010418 @default.
- W1998889274 hasRelatedWork W1994814773 @default.
- W1998889274 hasRelatedWork W2022309796 @default.
- W1998889274 hasRelatedWork W2041836123 @default.
- W1998889274 hasRelatedWork W2056064623 @default.
- W1998889274 hasRelatedWork W2059297585 @default.
- W1998889274 hasRelatedWork W2062402790 @default.
- W1998889274 hasRelatedWork W2079687938 @default.
- W1998889274 hasRelatedWork W2086951715 @default.
- W1998889274 hasRelatedWork W2227446639 @default.
- W1998889274 hasRelatedWork W2313121551 @default.
- W1998889274 hasRelatedWork W2409687946 @default.
- W1998889274 hasRelatedWork W2410370100 @default.
- W1998889274 hasRelatedWork W2419254430 @default.
- W1998889274 hasRelatedWork W2443601563 @default.
- W1998889274 hasRelatedWork W2479901905 @default.
- W1998889274 hasRelatedWork W840788495 @default.
- W1998889274 isParatext "false" @default.
- W1998889274 isRetracted "false" @default.
- W1998889274 magId "1998889274" @default.
- W1998889274 workType "article" @default.