Matches in SemOpenAlex for { <https://semopenalex.org/work/W1998889605> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W1998889605 endingPage "571" @default.
- W1998889605 startingPage "564" @default.
- W1998889605 abstract "The prognostic factors of short- and long-term survival have been studied in 352 patients with aplastic anemia of all grades of severity. This group was homogeneous with regard to the clinical and laboratory survey, and the treatment used (high-dose androgen therapy). The “hierarchy” of the individual prognostic parameters has been established: current severe infection, granulocyte count, percentage of the nonmyeloid cells on the bone marrow slides, platelet count, reticulocyte count, 59Fe utilization, and stromal disorganization on the bone marrow biopsy specimen. As these parameters are interrelated, a multiparametric analysis enables us to define groups of patients with different short-term evolution and to derive a prognostic index from these data. The use of such an index, however, allows a correct prediction in only 73 per cent of the cases, better in the milder than in the more severe cases. It is possible that the short-term evolutive tendency (improvement or worsening during the first six weeks of therapy) may contribute supplementary information useful for prognosis and the choice of treatment. After the first three months critical period, the mortality rate no longer depends on the initial severity of the disease but exclusively on the clinical and hematologic improvement. Thus, comparing the hematologic data obtained initially and after three months of androgen therapy allows us to correctly predict the long-term evolution." @default.
- W1998889605 created "2016-06-24" @default.
- W1998889605 creator A5080772622 @default.
- W1998889605 creator A5089543588 @default.
- W1998889605 date "1979-10-01" @default.
- W1998889605 modified "2023-09-25" @default.
- W1998889605 title "Prognostic factors in acquired aplastic anemia" @default.
- W1998889605 cites W101289525 @default.
- W1998889605 cites W1490072157 @default.
- W1998889605 cites W1963738039 @default.
- W1998889605 cites W1978687603 @default.
- W1998889605 cites W1982623896 @default.
- W1998889605 cites W1992033577 @default.
- W1998889605 cites W1995318454 @default.
- W1998889605 cites W2017529692 @default.
- W1998889605 cites W2037596769 @default.
- W1998889605 cites W2043228542 @default.
- W1998889605 cites W2054653558 @default.
- W1998889605 cites W2061954236 @default.
- W1998889605 cites W2078129461 @default.
- W1998889605 cites W2079207982 @default.
- W1998889605 cites W2081867373 @default.
- W1998889605 cites W2083863239 @default.
- W1998889605 cites W2087568857 @default.
- W1998889605 cites W2165858236 @default.
- W1998889605 cites W2253015249 @default.
- W1998889605 cites W2264606536 @default.
- W1998889605 cites W2315513195 @default.
- W1998889605 cites W2324309783 @default.
- W1998889605 cites W2327913243 @default.
- W1998889605 cites W2401716759 @default.
- W1998889605 cites W2405403753 @default.
- W1998889605 cites W2410234043 @default.
- W1998889605 cites W2411464566 @default.
- W1998889605 cites W2412006162 @default.
- W1998889605 cites W2415542092 @default.
- W1998889605 cites W2425503052 @default.
- W1998889605 cites W2429095331 @default.
- W1998889605 cites W2470401749 @default.
- W1998889605 cites W50319431 @default.
- W1998889605 doi "https://doi.org/10.1016/0002-9343(79)90226-2" @default.
- W1998889605 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/495627" @default.
- W1998889605 hasPublicationYear "1979" @default.
- W1998889605 type Work @default.
- W1998889605 sameAs 1998889605 @default.
- W1998889605 citedByCount "32" @default.
- W1998889605 countsByYear W19988896052012 @default.
- W1998889605 countsByYear W19988896052014 @default.
- W1998889605 countsByYear W19988896052017 @default.
- W1998889605 crossrefType "journal-article" @default.
- W1998889605 hasAuthorship W1998889605A5080772622 @default.
- W1998889605 hasAuthorship W1998889605A5089543588 @default.
- W1998889605 hasConcept C109159458 @default.
- W1998889605 hasConcept C126322002 @default.
- W1998889605 hasConcept C143998085 @default.
- W1998889605 hasConcept C2778248108 @default.
- W1998889605 hasConcept C2780007613 @default.
- W1998889605 hasConcept C2780525284 @default.
- W1998889605 hasConcept C2781440808 @default.
- W1998889605 hasConcept C28328180 @default.
- W1998889605 hasConcept C54355233 @default.
- W1998889605 hasConcept C71924100 @default.
- W1998889605 hasConcept C86803240 @default.
- W1998889605 hasConceptScore W1998889605C109159458 @default.
- W1998889605 hasConceptScore W1998889605C126322002 @default.
- W1998889605 hasConceptScore W1998889605C143998085 @default.
- W1998889605 hasConceptScore W1998889605C2778248108 @default.
- W1998889605 hasConceptScore W1998889605C2780007613 @default.
- W1998889605 hasConceptScore W1998889605C2780525284 @default.
- W1998889605 hasConceptScore W1998889605C2781440808 @default.
- W1998889605 hasConceptScore W1998889605C28328180 @default.
- W1998889605 hasConceptScore W1998889605C54355233 @default.
- W1998889605 hasConceptScore W1998889605C71924100 @default.
- W1998889605 hasConceptScore W1998889605C86803240 @default.
- W1998889605 hasIssue "4" @default.
- W1998889605 hasLocation W19988896051 @default.
- W1998889605 hasLocation W19988896052 @default.
- W1998889605 hasOpenAccess W1998889605 @default.
- W1998889605 hasPrimaryLocation W19988896051 @default.
- W1998889605 hasRelatedWork W1965001236 @default.
- W1998889605 hasRelatedWork W1983264920 @default.
- W1998889605 hasRelatedWork W2074712187 @default.
- W1998889605 hasRelatedWork W2125837235 @default.
- W1998889605 hasRelatedWork W2383468041 @default.
- W1998889605 hasRelatedWork W2500019632 @default.
- W1998889605 hasRelatedWork W2573487694 @default.
- W1998889605 hasRelatedWork W2756176868 @default.
- W1998889605 hasRelatedWork W2880625729 @default.
- W1998889605 hasRelatedWork W3023386604 @default.
- W1998889605 hasVolume "67" @default.
- W1998889605 isParatext "false" @default.
- W1998889605 isRetracted "false" @default.
- W1998889605 magId "1998889605" @default.
- W1998889605 workType "article" @default.