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• W1998935810 abstract "A new series of substituted 2-sulfonyphenyl-3-phenyl-indole derivatives were synthesized and evaluated for their ability to inhibit COX-2 and COX-1enzymes. Most of the compounds synthesized were found to be highly potent and selective inhibitors of COX-2. This work led to the discovery of 2-aminosulfonylphenyl-3-phenyl-indole 5a which possesses higher activity and selectivity for COX-2 than Celecoxib both in vitro and in vivo." @default.
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• W1998935810 date "2003-04-01" @default.
• W1998935810 modified "2023-09-28" @default.
• W1998935810 title "Synthesis and biological evaluation of substituted 2-sulfonyl-phenyl-3-phenyl-indoles: a new series of selective COX-2 inhibitors" @default.
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• W1998935810 doi "https://doi.org/10.1016/s0968-0896(03)00046-4" @default.
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