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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1998957232> ?p ?o ?g. }

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• W1998957232 abstract "Five new anti-trypanosomal macrolides, actinoallolides A–E (1–5), were discovered from the cultured broth of Actinoallomurus fulvus MK10-036. The structures of the actinoallolides, including absolute stereochemistry, were elucidated by a combination of spectroscopic analyses and a series of chemical derivatization studies. Actinoallolide A showed the most potent and selective in vitro anti-trypanosomal activity without cytotoxicity. A new class of promising lead compounds was identified for the development of drugs for both sleeping sickness and Chagas disease." @default.
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• W1998957232 date "2015-01-30" @default.
• W1998957232 modified "2023-09-26" @default.
• W1998957232 title "Actinoallolides A–E, New Anti-trypanosomal Macrolides, Produced by an Endophytic Actinomycete, <i>Actinoallomurus fulvus</i> MK10-036" @default.
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• W1998957232 doi "https://doi.org/10.1021/ol5037216" @default.
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