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• W1999024211 abstract "To investigate whether red wine and green tea could exert anti-H pylori or anti-VacA activity in vivo in a mouse model of experimental infection.Ethanol-free red wine and green tea concentrates were administered orally as a mixture of the two beverages to H pylori infected mice, or separately to VacA-treated mice. Gastric colonization and gastric inflammation were quantified by microbiological, histopathological, and immunohistochemical analyses.In H pylori-infected mice, the red wine and green tea mixture significantly prevented gastritis and limited the localization of bacteria and VacA to the surface of the gastric epithelium. Similarly, both beverages significantly prevented gastric epithelium damage in VacA-treated mice; green tea, but not red wine, also altered the VacA localization in the gastric epithelium.Red wine and green tea are able to prevent H pylori-induced gastric epithelium damage, possibly involving VacA inhibition. This observation supports the possible relevance of diet on the pathological outcome of H pylori infection." @default.
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• W1999024211 date "2007-01-01" @default.
• W1999024211 modified "2023-10-17" @default.
• W1999024211 title "Red wine and green tea reduce<i>H pylori-</i>or<i>VacA-induced</i>gastritis in a mouse model" @default.
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• W1999024211 doi "https://doi.org/10.3748/wjg.v13.i3.349" @default.
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