FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1999044> ?p ?o ?g. }

• W1999044 endingPage "1764" @default.
• W1999044 startingPage "1757" @default.
• W1999044 abstract "Abstract Platelet involvement in adhesion, hemostasis, and immune adherence is mediated by functionally associated cell surface molecules. Platelets are also involved in cytolytic reactions, but little is known about the mechanisms or biologic significance of these processes. To further investigate cell surface molecules concerned with platelet function, antisera against mouse platelets, thymocytes, and macrophages and monoclonal antibodies against Mac-1 (complement receptor type 3) and leukocyte function-associated glycoprotein type 1 (LFA-1) were used to demonstrate LFA-1--like molecules on mouse platelets. The alpha subunits of platelet and thymocyte LFA-1 showed identical electrophoretic mobility but differed significantly from the alpha subunit of macrophage Mac-1. Peptide mapping demonstrated the identity of the beta subunits of these three molecules but showed that the alpha subunit of Mac-1 was distinct from the alpha subunits of platelet and thymocyte LFA-1. Platelet LFA-1, as demonstrated by surface iodination with lactoperoxidase and by labeling sialic acid residues with sodium borohydride, was not a major component of the platelet membrane. The functional significance of LFA-1 on mouse platelets has yet to be demonstrated, monoclonal antibodies against LFA-1 having little effect on adenosine diphosphate-induced platelet aggregation and immune adherence. In contrast, although Mac-1 could not be demonstrated on mouse platelets in immunoprecipitation studies, its presence was clearly demonstrated by low levels of antibody binding in enzyme-linked immunosorbent assays and by the ability of M1/70 monoclonal antibody to inhibit platelet immune adherence. Human platelets, which are inactive in immune adherence assays, are shown to lack LFA-1 and Mac-1." @default.
• W1999044 created "2016-06-24" @default.
• W1999044 creator A5037680649 @default.
• W1999044 creator A5073562170 @default.
• W1999044 date "1986-06-01" @default.
• W1999044 modified "2023-10-03" @default.
• W1999044 title "Expression of the leukocyte functional molecule (LFA-1) on mouse platelets" @default.
• W1999044 cites W1520029826 @default.
• W1999044 cites W1528682116 @default.
• W1999044 cites W1594676787 @default.
• W1999044 cites W1667309983 @default.
• W1999044 cites W169435351 @default.
• W1999044 cites W1713253369 @default.
• W1999044 cites W1725113599 @default.
• W1999044 cites W1789296762 @default.
• W1999044 cites W1936995585 @default.
• W1999044 cites W1970654518 @default.
• W1999044 cites W1977277445 @default.
• W1999044 cites W1982763922 @default.
• W1999044 cites W1987262605 @default.
• W1999044 cites W2001035036 @default.
• W1999044 cites W2023318533 @default.
• W1999044 cites W2062147146 @default.
• W1999044 cites W2066055990 @default.
• W1999044 cites W2075032348 @default.
• W1999044 cites W2076300996 @default.
• W1999044 cites W2077702220 @default.
• W1999044 cites W2080226094 @default.
• W1999044 cites W2086864461 @default.
• W1999044 cites W2100837269 @default.
• W1999044 cites W2118531513 @default.
• W1999044 cites W2135212714 @default.
• W1999044 cites W2142488029 @default.
• W1999044 cites W2164358316 @default.
• W1999044 cites W2168315486 @default.
• W1999044 cites W2310464721 @default.
• W1999044 cites W2415390855 @default.
• W1999044 cites W2420742233 @default.
• W1999044 doi "https://doi.org/10.1182/blood.v67.6.1757.1757" @default.
• W1999044 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3518835" @default.
• W1999044 hasPublicationYear "1986" @default.
• W1999044 type Work @default.
• W1999044 sameAs 1999044 @default.
• W1999044 citedByCount "29" @default.
• W1999044 countsByYear W19990442013 @default.
• W1999044 countsByYear W19990442015 @default.
• W1999044 countsByYear W19990442017 @default.
• W1999044 crossrefType "journal-article" @default.
• W1999044 hasAuthorship W1999044A5037680649 @default.
• W1999044 hasAuthorship W1999044A5073562170 @default.
• W1999044 hasBestOaLocation W19990441 @default.
• W1999044 hasConcept C153911025 @default.
• W1999044 hasConcept C159654299 @default.
• W1999044 hasConcept C185592680 @default.
• W1999044 hasConcept C203014093 @default.
• W1999044 hasConcept C2776090121 @default.
• W1999044 hasConcept C2778212101 @default.
• W1999044 hasConcept C2778954852 @default.
• W1999044 hasConcept C3018697912 @default.
• W1999044 hasConcept C34343649 @default.
• W1999044 hasConcept C542903549 @default.
• W1999044 hasConcept C55493867 @default.
• W1999044 hasConcept C71829478 @default.
• W1999044 hasConcept C86803240 @default.
• W1999044 hasConcept C8891405 @default.
• W1999044 hasConcept C89560881 @default.
• W1999044 hasConceptScore W1999044C153911025 @default.
• W1999044 hasConceptScore W1999044C159654299 @default.
• W1999044 hasConceptScore W1999044C185592680 @default.
• W1999044 hasConceptScore W1999044C203014093 @default.
• W1999044 hasConceptScore W1999044C2776090121 @default.
• W1999044 hasConceptScore W1999044C2778212101 @default.
• W1999044 hasConceptScore W1999044C2778954852 @default.
• W1999044 hasConceptScore W1999044C3018697912 @default.
• W1999044 hasConceptScore W1999044C34343649 @default.
• W1999044 hasConceptScore W1999044C542903549 @default.
• W1999044 hasConceptScore W1999044C55493867 @default.
• W1999044 hasConceptScore W1999044C71829478 @default.
• W1999044 hasConceptScore W1999044C86803240 @default.
• W1999044 hasConceptScore W1999044C8891405 @default.
• W1999044 hasConceptScore W1999044C89560881 @default.
• W1999044 hasIssue "6" @default.
• W1999044 hasLocation W19990441 @default.
• W1999044 hasOpenAccess W1999044 @default.
• W1999044 hasPrimaryLocation W19990441 @default.
• W1999044 hasRelatedWork W199672269 @default.
• W1999044 hasRelatedWork W2125720915 @default.
• W1999044 hasRelatedWork W2145080200 @default.
• W1999044 hasRelatedWork W2361454127 @default.
• W1999044 hasRelatedWork W2368460920 @default.
• W1999044 hasRelatedWork W2375345506 @default.
• W1999044 hasRelatedWork W2380360044 @default.
• W1999044 hasRelatedWork W2383357146 @default.
• W1999044 hasRelatedWork W2398252525 @default.
• W1999044 hasRelatedWork W2741987483 @default.
• W1999044 hasVolume "67" @default.
• W1999044 isParatext "false" @default.
• W1999044 isRetracted "false" @default.

• next