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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1999079290> ?p ?o ?g. }

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• W1999079290 abstract "Novel series of N-benzyl 1,4-dihydropyridines have been prepared by facile syntheses. All relevant substituents of the molecular scaffold have been varied. The resulting compounds were biologically evaluated as P-glycoprotein (P-gp) inhibitors. Substitutions of the N-benzyl residue favour biological activity beside respective 3-ester functions. Most active compounds were further evaluated as multidrug resistance (MDR) modulators to restore the cytotoxic properties of varying daunorubicin applications." @default.
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• W1999079290 date "2013-01-01" @default.
• W1999079290 modified "2023-10-11" @default.
• W1999079290 title "Development of small-molecule P-gp inhibitors of the N-benzyl 1,4-dihydropyridine type: Novel aspects in SAR and bioanalytical evaluation of multidrug resistance (MDR) reversal properties" @default.
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• W1999079290 doi "https://doi.org/10.1016/j.bmc.2012.10.041" @default.
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