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- W1999080438 abstract "Many pathologic processes that accelerate the progression of heart failure, such as cardiac remodeling and impaired contractility, may be modulated by administration of recombinant growth hormone. The agent improves structural and functional aspects of the failing heart both in the short term and after several months of therapy. However, conflicting clinical results cast doubt on whether it has a clear benefit in all of these patients. In addition, growth hormone therapy may be associated with cardiac and noncardiac adverse effects. Many questions must be addressed before its place in heart failure therapy is established. Optimal patient population, dosing regimen, duration of therapy, and effect on patient survival are unknown. Until larger, blinded studies are completed, growth hormone therapy remains an investigational approach to managing refractory heart failure." @default.
- W1999080438 created "2016-06-24" @default.
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- W1999080438 date "2000-09-01" @default.
- W1999080438 modified "2023-09-26" @default.
- W1999080438 title "Growth Hormone: A Promising Treatment for the Failing Heart?" @default.
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- W1999080438 doi "https://doi.org/10.1592/phco.20.13.1096.35035" @default.
- W1999080438 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10999503" @default.
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