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- W1999080887 abstract "The effects of corticotropin-releasing factor (CRF) on pentobarbital-induced sleeping time and hypothermia in rats were studied. Intraventricular administration of CRF significantly shortened the sleeping time induced by pentobarbital injection (50 mg/kg b.wt.) in a dose-dependent manner. CRF also attenuated the hypothermic effect of pentobarbital. However, peripheral administration of CRF did not affect the action of pentobarbital. alpha-Helical CRF9-41, CRF antagonist, reversed the effects of CRF. These results suggest that CRF antagonizes the effects of pentobarbital within the central nervous system." @default.
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- W1999080887 date "1986-09-01" @default.
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- W1999080887 title "The antagonistic effect of corticotropin-releasing factor on pentobarbital in rats" @default.
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- W1999080887 doi "https://doi.org/10.1016/0006-8993(86)90033-8" @default.
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