FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1999089265> ?p ?o ?g. }

• W1999089265 endingPage "406" @default.
• W1999089265 startingPage "405" @default.
• W1999089265 abstract "P592 The Model of End-Stage Liver Disease (MELD) scoring system is the current standard for determining recipient priority for liver transplantation. Under this scoring system, a patient diagnosed with hepatocellular carcinoma (HCC) receives a considerable increase in their priority score. As a result, multiple programs have adopted an aggressive surveillance program, which frequently utilizes surgical exploration, to confirm the presence of and provide treatment for tumors. Methods: All potential liver transplant candidates who were explored for a radiographic mass were identified, and patient demographics, tumor characteristics and patient survivals were examined. All patients with tumors identified by intra-operative ultrasound underwent radiofrequency ablation (RFA). Results: Sixty-four patients were explored for undiagnosed liver masses. Three (7%) patients were managed via an open incision; one laparoscopic patient required conversion to improve access to safely ablate a dome lesion. Fourteen (21%) patients underwent laparoscopy without ablation: absence of diagnostic lesions (n=7), metastatic disease (n=5), or benign tumor biopsy (n=2). Mean hospital stay for the series was 36 hours (range 20 to 50 hrs). Complications included new onset of ascites (n=5), worsening of ascites (n=23), and wound infection (n=4). No treatment related mortality was incurred. Of the 46 patients who received RFA, 16 (34%) were excluded from transplantation: newly diagnosed pulmonary hypertension (n=2), unabated alcohol usage (n=2), poor physiologic age (n=2), lack of social support (n=5), morbid obesity (n=2), metastatic disease (n=1), and death [variceal bleed, recurrent HCC] (n=2). Twenty-seven (42%) explored patients were transplanted, while 9 (14%) patients were excluded from transplantation based on findings identified during the procedure. With the diagnosis of HCC, 24 patients in need of therapeutic transplantation had their MELD scores increased from 14 to 22 points. Six patients are currently awaiting either completion of their evaluations or transplantation. Time from RFA to transplant ranged from 2 weeks to 1 year. Examination of explants identified one (2%) liver in which HCC was missed. Of the 24 patients who underwent RFA, all had evidence of necrosis, which varied from 30 to 99%. While those with RFA-to-transplant intervals greater than 3 months had the highest percentages of necrosis, those with shorter intervals, though demonstrating lower percentages of necrosis, displayed extensive apoptotic tumors. Conclusion: Laparoscopic evaluation and RFA of hepatic tumors in cirrhotic transplant candidates is both safe and efficacious. With continued changes in the MELD scoring system, laparoscopy can provide both accurate staging and interventional therapy for candidates awaiting transplantation. In this series, laparoscopic findings saved 14% of patients from an unnecessary open exploration at the time of organ availability. The findings of this series also indicate there is a linear rate of necrosis found in cirrhotic livers after ablation." @default.
• W1999089265 created "2016-06-24" @default.
• W1999089265 creator A5007797174 @default.
• W1999089265 creator A5014670558 @default.
• W1999089265 creator A5015339912 @default.
• W1999089265 creator A5020126018 @default.
• W1999089265 creator A5054506083 @default.
• W1999089265 creator A5059910786 @default.
• W1999089265 creator A5061584208 @default.
• W1999089265 creator A5063239029 @default.
• W1999089265 creator A5081131162 @default.
• W1999089265 creator A5083564288 @default.
• W1999089265 creator A5084956027 @default.
• W1999089265 creator A5090225246 @default.
• W1999089265 date "2004-07-01" @default.
• W1999089265 modified "2023-10-14" @default.
• W1999089265 title "LAPAROSCOPIC EVALUATION OF MASSES IN END STAGE LIVER DISEASE PATIENTS" @default.
• W1999089265 doi "https://doi.org/10.1097/00007890-200407271-01087" @default.
• W1999089265 hasPublicationYear "2004" @default.
• W1999089265 type Work @default.
• W1999089265 sameAs 1999089265 @default.
• W1999089265 citedByCount "0" @default.
• W1999089265 crossrefType "journal-article" @default.
• W1999089265 hasAuthorship W1999089265A5007797174 @default.
• W1999089265 hasAuthorship W1999089265A5014670558 @default.
• W1999089265 hasAuthorship W1999089265A5015339912 @default.
• W1999089265 hasAuthorship W1999089265A5020126018 @default.
• W1999089265 hasAuthorship W1999089265A5054506083 @default.
• W1999089265 hasAuthorship W1999089265A5059910786 @default.
• W1999089265 hasAuthorship W1999089265A5061584208 @default.
• W1999089265 hasAuthorship W1999089265A5063239029 @default.
• W1999089265 hasAuthorship W1999089265A5081131162 @default.
• W1999089265 hasAuthorship W1999089265A5083564288 @default.
• W1999089265 hasAuthorship W1999089265A5084956027 @default.
• W1999089265 hasAuthorship W1999089265A5090225246 @default.
• W1999089265 hasConcept C126322002 @default.
• W1999089265 hasConcept C126838900 @default.
• W1999089265 hasConcept C141071460 @default.
• W1999089265 hasConcept C146357865 @default.
• W1999089265 hasConcept C151730666 @default.
• W1999089265 hasConcept C2775934546 @default.
• W1999089265 hasConcept C2777075537 @default.
• W1999089265 hasConcept C2777377203 @default.
• W1999089265 hasConcept C2778019345 @default.
• W1999089265 hasConcept C2778902805 @default.
• W1999089265 hasConcept C2779609443 @default.
• W1999089265 hasConcept C2780047204 @default.
• W1999089265 hasConcept C2780496750 @default.
• W1999089265 hasConcept C2911091166 @default.
• W1999089265 hasConcept C71924100 @default.
• W1999089265 hasConcept C86803240 @default.
• W1999089265 hasConceptScore W1999089265C126322002 @default.
• W1999089265 hasConceptScore W1999089265C126838900 @default.
• W1999089265 hasConceptScore W1999089265C141071460 @default.
• W1999089265 hasConceptScore W1999089265C146357865 @default.
• W1999089265 hasConceptScore W1999089265C151730666 @default.
• W1999089265 hasConceptScore W1999089265C2775934546 @default.
• W1999089265 hasConceptScore W1999089265C2777075537 @default.
• W1999089265 hasConceptScore W1999089265C2777377203 @default.
• W1999089265 hasConceptScore W1999089265C2778019345 @default.
• W1999089265 hasConceptScore W1999089265C2778902805 @default.
• W1999089265 hasConceptScore W1999089265C2779609443 @default.
• W1999089265 hasConceptScore W1999089265C2780047204 @default.
• W1999089265 hasConceptScore W1999089265C2780496750 @default.
• W1999089265 hasConceptScore W1999089265C2911091166 @default.
• W1999089265 hasConceptScore W1999089265C71924100 @default.
• W1999089265 hasConceptScore W1999089265C86803240 @default.
• W1999089265 hasLocation W19990892651 @default.
• W1999089265 hasOpenAccess W1999089265 @default.
• W1999089265 hasPrimaryLocation W19990892651 @default.
• W1999089265 hasRelatedWork W159125119 @default.
• W1999089265 hasRelatedWork W2029017645 @default.
• W1999089265 hasRelatedWork W2084094406 @default.
• W1999089265 hasRelatedWork W2093365253 @default.
• W1999089265 hasRelatedWork W2101903089 @default.
• W1999089265 hasRelatedWork W2386253513 @default.
• W1999089265 hasRelatedWork W2804421369 @default.
• W1999089265 hasRelatedWork W2892230278 @default.
• W1999089265 hasRelatedWork W4246287754 @default.
• W1999089265 hasRelatedWork W2185155109 @default.
• W1999089265 hasVolume "78" @default.
• W1999089265 isParatext "false" @default.
• W1999089265 isRetracted "false" @default.
• W1999089265 magId "1999089265" @default.
• W1999089265 workType "article" @default.