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- W1999098315 endingPage "316" @default.
- W1999098315 startingPage "285" @default.
- W1999098315 abstract "Recombinant DNA-derived proteins and, in particular, human pituitary hormones, are increasingly used for research, diagnostic and therapeutic purposes. This trend has demanded new synthetic approaches and improved purification techniques. The type and sequence of the purification steps have to be selected in accordance with the cloning and protein expression strategy, the host organism and cellular localization of the protein of interest, with a view to producing the desired product at a required purity, biological activity and acceptable cost. This review article describes and analyzes the main synthetic and purification strategies that have been used for the production of recombinant human growth hormone, prolactin, thyrotropin, luteinizing hormone and follicle-stimulating hormone, giving special consideration to the few published downstream processes utilized by the biotechnology industry. Practically all types of prokaryotic and eukaryotic organisms utilized for this purpose are also reviewed." @default.
- W1999098315 created "2016-06-24" @default.
- W1999098315 creator A5044420183 @default.
- W1999098315 creator A5074428262 @default.
- W1999098315 creator A5084992404 @default.
- W1999098315 date "2003-06-01" @default.
- W1999098315 modified "2023-10-10" @default.
- W1999098315 title "Synthesis and chromatographic purification of recombinant human pituitary hormones" @default.
- W1999098315 cites W140599878 @default.
- W1999098315 cites W1483226634 @default.
- W1999098315 cites W1499276444 @default.
- W1999098315 cites W1505517942 @default.
- W1999098315 cites W1514815542 @default.
- W1999098315 cites W1529950285 @default.
- W1999098315 cites W1535133733 @default.
- W1999098315 cites W1539409018 @default.
- W1999098315 cites W1541323919 @default.
- W1999098315 cites W1548416905 @default.
- W1999098315 cites W1565160468 @default.
- W1999098315 cites W1566158288 @default.
- W1999098315 cites W1572066007 @default.
- W1999098315 cites W1602847006 @default.
- W1999098315 cites W1625675389 @default.
- W1999098315 cites W1674837479 @default.
- W1999098315 cites W1784417788 @default.
- W1999098315 cites W193202476 @default.
- W1999098315 cites W1964452273 @default.
- W1999098315 cites W1965645275 @default.
- W1999098315 cites W1966707933 @default.
- W1999098315 cites W1966710497 @default.
- W1999098315 cites W1969568676 @default.
- W1999098315 cites W1970169630 @default.
- W1999098315 cites W1970960314 @default.
- W1999098315 cites W1971281264 @default.
- W1999098315 cites W1971737131 @default.
- W1999098315 cites W1971951830 @default.
- W1999098315 cites W1972526061 @default.
- W1999098315 cites W1972620015 @default.
- W1999098315 cites W1974351567 @default.
- W1999098315 cites W1975085348 @default.
- W1999098315 cites W1975699819 @default.
- W1999098315 cites W1975791081 @default.
- W1999098315 cites W197617682 @default.
- W1999098315 cites W1976659956 @default.
- W1999098315 cites W1980703229 @default.
- W1999098315 cites W1982124897 @default.
- W1999098315 cites W1982178202 @default.
- W1999098315 cites W1985748539 @default.
- W1999098315 cites W1986136768 @default.
- W1999098315 cites W1987166857 @default.
- W1999098315 cites W1987687120 @default.
- W1999098315 cites W1988076022 @default.
- W1999098315 cites W1988351276 @default.
- W1999098315 cites W1989429684 @default.
- W1999098315 cites W1989448227 @default.
- W1999098315 cites W1990365349 @default.
- W1999098315 cites W1991914963 @default.
- W1999098315 cites W1992092712 @default.
- W1999098315 cites W1992155962 @default.
- W1999098315 cites W1994416898 @default.
- W1999098315 cites W1995013658 @default.
- W1999098315 cites W1995994862 @default.
- W1999098315 cites W1996820650 @default.
- W1999098315 cites W1997027462 @default.
- W1999098315 cites W1998023346 @default.
- W1999098315 cites W1998092526 @default.
- W1999098315 cites W1999254684 @default.
- W1999098315 cites W2001267348 @default.
- W1999098315 cites W2003226934 @default.
- W1999098315 cites W2003627674 @default.
- W1999098315 cites W2004304814 @default.
- W1999098315 cites W2004394343 @default.
- W1999098315 cites W2004459900 @default.
- W1999098315 cites W2004597017 @default.
- W1999098315 cites W2004950955 @default.
- W1999098315 cites W2006103103 @default.
- W1999098315 cites W2006605671 @default.
- W1999098315 cites W2006665242 @default.
- W1999098315 cites W2008205277 @default.
- W1999098315 cites W2010476490 @default.
- W1999098315 cites W2010748293 @default.
- W1999098315 cites W2010818113 @default.
- W1999098315 cites W2010941308 @default.
- W1999098315 cites W2011025411 @default.
- W1999098315 cites W2011774449 @default.
- W1999098315 cites W2012420609 @default.
- W1999098315 cites W2012891427 @default.
- W1999098315 cites W2015139192 @default.
- W1999098315 cites W2015242294 @default.
- W1999098315 cites W2015462411 @default.
- W1999098315 cites W2016438365 @default.
- W1999098315 cites W2016692882 @default.
- W1999098315 cites W2017550212 @default.
- W1999098315 cites W2018122709 @default.
- W1999098315 cites W2019472675 @default.
- W1999098315 cites W2019809373 @default.
- W1999098315 cites W2019948721 @default.
- W1999098315 cites W2021020896 @default.