FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1999131819> ?p ?o ?g. }

• W1999131819 endingPage "3854" @default.
• W1999131819 startingPage "3848" @default.
• W1999131819 abstract "ABSTRACT The arginine regulatory protein of Pseudomonas aeruginosa , ArgR, is essential for induction of operons that encode enzymes of the arginine succinyltransferase (AST) pathway, which is the primary route for arginine utilization by this organism under aerobic conditions. ArgR also induces the operon that encodes a catabolic NAD + -dependent glutamate dehydrogenase (GDH), which converts l -glutamate, the product of the AST pathway, in α-ketoglutarate. The studies reported here show that ArgR also participates in the regulation of other enzymes of glutamate metabolism. Exogenous arginine repressed the specific activities of glutamate synthase (GltBD) and anabolic NADP-dependent GDH (GdhA) in cell extracts of strain PAO1, and this repression was abolished in an argR mutant. The promoter regions of the gltBD operon, which encodes GltBD, and the gdhA gene, which encodes GdhA, were identified by primer extension experiments. Measurements of β-galactosidase expression from gltB :: lacZ and gdhA :: lacZ translational fusions confirmed the role of ArgR in mediating arginine repression. Gel retardation assays demonstrated the binding of homogeneous ArgR to DNA fragments carrying the regulatory regions for the gltBD and gdhA genes. DNase I footprinting experiments showed that ArgR protects DNA sequences in the control regions for these genes that are homologous to the consensus sequence of the ArgR binding site. In silica analysis of genomic information for P . fluorescens , P . putida , and P . stutzeri suggests that the findings reported here regarding ArgR regulation of operons that encode enzymes of glutamate biosynthesis in P . aeruginosa likely apply to other pseudomonads." @default.
• W1999131819 created "2016-06-24" @default.
• W1999131819 creator A5000728212 @default.
• W1999131819 creator A5029060020 @default.
• W1999131819 creator A5050241651 @default.
• W1999131819 creator A5073173002 @default.
• W1999131819 date "2004-06-15" @default.
• W1999131819 modified "2023-09-29" @default.
• W1999131819 title "The Arginine Regulatory Protein Mediates Repression by Arginine of the Operons Encoding Glutamate Synthase and Anabolic Glutamate Dehydrogenase in <i>Pseudomonas aeruginosa</i>" @default.
• W1999131819 cites W1486968353 @default.
• W1999131819 cites W1489352271 @default.
• W1999131819 cites W1517780016 @default.
• W1999131819 cites W1643238181 @default.
• W1999131819 cites W1655788596 @default.
• W1999131819 cites W1665661757 @default.
• W1999131819 cites W1773589470 @default.
• W1999131819 cites W1794839330 @default.
• W1999131819 cites W1940825484 @default.
• W1999131819 cites W1967329874 @default.
• W1999131819 cites W1969493916 @default.
• W1999131819 cites W1984469772 @default.
• W1999131819 cites W1994106479 @default.
• W1999131819 cites W2001979955 @default.
• W1999131819 cites W2007457312 @default.
• W1999131819 cites W2008417292 @default.
• W1999131819 cites W2018010694 @default.
• W1999131819 cites W2028796319 @default.
• W1999131819 cites W203476929 @default.
• W1999131819 cites W2042487430 @default.
• W1999131819 cites W2061166930 @default.
• W1999131819 cites W2079631800 @default.
• W1999131819 cites W2098164977 @default.
• W1999131819 cites W2101125257 @default.
• W1999131819 cites W2107082879 @default.
• W1999131819 cites W2128635872 @default.
• W1999131819 cites W2140663847 @default.
• W1999131819 cites W2147987449 @default.
• W1999131819 cites W2148922163 @default.
• W1999131819 cites W2160027305 @default.
• W1999131819 cites W4293247451 @default.
• W1999131819 doi "https://doi.org/10.1128/jb.186.12.3848-3854.2004" @default.
• W1999131819 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/419967" @default.
• W1999131819 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15175298" @default.
• W1999131819 hasPublicationYear "2004" @default.
• W1999131819 type Work @default.
• W1999131819 sameAs 1999131819 @default.
• W1999131819 citedByCount "23" @default.
• W1999131819 countsByYear W19991318192012 @default.
• W1999131819 countsByYear W19991318192013 @default.
• W1999131819 countsByYear W19991318192014 @default.
• W1999131819 countsByYear W19991318192016 @default.
• W1999131819 countsByYear W19991318192017 @default.
• W1999131819 countsByYear W19991318192018 @default.
• W1999131819 countsByYear W19991318192019 @default.
• W1999131819 countsByYear W19991318192023 @default.
• W1999131819 crossrefType "journal-article" @default.
• W1999131819 hasAuthorship W1999131819A5000728212 @default.
• W1999131819 hasAuthorship W1999131819A5029060020 @default.
• W1999131819 hasAuthorship W1999131819A5050241651 @default.
• W1999131819 hasAuthorship W1999131819A5073173002 @default.
• W1999131819 hasBestOaLocation W19991318191 @default.
• W1999131819 hasConcept C104317684 @default.
• W1999131819 hasConcept C143065580 @default.
• W1999131819 hasConcept C150194340 @default.
• W1999131819 hasConcept C158448853 @default.
• W1999131819 hasConcept C170493617 @default.
• W1999131819 hasConcept C186310378 @default.
• W1999131819 hasConcept C203075996 @default.
• W1999131819 hasConcept C2777202666 @default.
• W1999131819 hasConcept C55493867 @default.
• W1999131819 hasConcept C61174792 @default.
• W1999131819 hasConcept C73766848 @default.
• W1999131819 hasConcept C86803240 @default.
• W1999131819 hasConceptScore W1999131819C104317684 @default.
• W1999131819 hasConceptScore W1999131819C143065580 @default.
• W1999131819 hasConceptScore W1999131819C150194340 @default.
• W1999131819 hasConceptScore W1999131819C158448853 @default.
• W1999131819 hasConceptScore W1999131819C170493617 @default.
• W1999131819 hasConceptScore W1999131819C186310378 @default.
• W1999131819 hasConceptScore W1999131819C203075996 @default.
• W1999131819 hasConceptScore W1999131819C2777202666 @default.
• W1999131819 hasConceptScore W1999131819C55493867 @default.
• W1999131819 hasConceptScore W1999131819C61174792 @default.
• W1999131819 hasConceptScore W1999131819C73766848 @default.
• W1999131819 hasConceptScore W1999131819C86803240 @default.
• W1999131819 hasIssue "12" @default.
• W1999131819 hasLocation W19991318191 @default.
• W1999131819 hasLocation W19991318192 @default.
• W1999131819 hasLocation W19991318193 @default.
• W1999131819 hasLocation W19991318194 @default.
• W1999131819 hasOpenAccess W1999131819 @default.
• W1999131819 hasPrimaryLocation W19991318191 @default.
• W1999131819 hasRelatedWork W1837413175 @default.
• W1999131819 hasRelatedWork W1855310881 @default.
• W1999131819 hasRelatedWork W1873997157 @default.
• W1999131819 hasRelatedWork W1976238592 @default.
• W1999131819 hasRelatedWork W1980579026 @default.
• W1999131819 hasRelatedWork W2165249808 @default.

• next