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- W1999202393 abstract "The distribution of cytochrome c oxidase, monoamine oxidase and lactate dehydrogenase, together with protein, after isopycnic centrifugation of a crude mitochondrial fraction of chick telencephalon homogenate in a linear sucrose density gradient, was followed during late embryogenesis and postnatal maturation. Two main populations of subcellular organelles differentiate; they were characterized biochemically and analyzed by electron microscopy. One population, with a progressively defined mean bouyant density of 1.170 g/ml, exhibited a high relative activity of monoamine oxidase, with a low and relatively constant cytochrome c oxidase/monoamine oxidase activity ratio. This population was composed of free mitochondria and mitochondria enclosed in nerve endings, and possibly of mitochondria of perikaryal and glial origin. A second population, with a progressively well defined mean buoyant density of 1.182–1.186 g/ml, exhibited a high relative activity of cytochrome c oxidase, with a high and increasing cytochrome c oxidase/monoamine oxidase activity ratio. The biochemical and functional significance of these results were discussed." @default.
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- W1999202393 date "1977-02-01" @default.
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- W1999202393 title "Subcellular distribution of cytochrome c oxidase, monoamine oxidase and lactate dehydrogenase in the developing chick telencephalon" @default.
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- W1999202393 doi "https://doi.org/10.1016/0006-8993(77)90459-0" @default.
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